SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)
2pzh HYPOTHETICAL PROTEIN
HP_0496

(Helicobacter
pylori)
4 / 7 TYR A  21
THR A  10
LEU A  66
VAL A   5
None
0.97A 2cppA-2pzhA:
undetectable
2cppA-2pzhA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)
2pzh HYPOTHETICAL PROTEIN
HP_0496

(Helicobacter
pylori)
5 / 12 LEU A  75
LEU A 130
ASN A 131
LEU A 129
GLN A  36
None
1.39A 3zqtA-2pzhA:
undetectable
3zqtA-2pzhA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
2pzh HYPOTHETICAL PROTEIN
HP_0496

(Helicobacter
pylori)
4 / 8 TYR A  21
THR A  10
LEU A  66
VAL A   5
None
0.96A 4l4aA-2pzhA:
undetectable
4l4aA-2pzhA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
2pzh HYPOTHETICAL PROTEIN
HP_0496

(Helicobacter
pylori)
4 / 8 TYR A  21
THR A  10
LEU A  66
VAL A   5
None
0.94A 4l4eA-2pzhA:
undetectable
4l4eA-2pzhA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
2pzh HYPOTHETICAL PROTEIN
HP_0496

(Helicobacter
pylori)
4 / 8 TYR A  21
THR A  10
LEU A  66
VAL A   5
None
0.95A 4l4fA-2pzhA:
undetectable
4l4fA-2pzhA:
15.22