SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 5 THR A 168
THR A 169
GLU A 174
HIS A 178
 None
 1.44A 1d4fB-2q01A:
undetectable		 1d4fB-2q01A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 5 THR A 169
ASP A 249
HIS A 307
HIS A  39
 None
 0.93A 1ei6A-2q01A:
undetectable		 1ei6A-2q01A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 8 THR A 169
ASP A 249
HIS A 307
HIS A  39
 None
 0.97A 1ei6C-2q01A:
undetectable		 1ei6C-2q01A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 8 THR A 169
ASP A 249
HIS A 307
HIS A  39
 None
 0.94A 1ei6D-2q01A:
undetectable		 1ei6D-2q01A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 8 ALA A 265
LEU A 272
HIS A 233
LEU A 230
 None
 0.91A 1ereE-2q01A:
undetectable		 1ereE-2q01A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 8 ALA A 265
LEU A 272
HIS A 233
LEU A 230
 None
 0.92A 1ereF-2q01A:
undetectable		 1ereF-2q01A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 10 ALA A 243
ALA A 245
LEU A 470
GLN A 472
GLN A 238
 None
 1.32A 1rlbE-2q01A:
undetectable		 1rlbE-2q01A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 6 TRP A  98
ASN A 135
LEU A 131
PHE A 121
 None
 1.44A 1ru9H-2q01A:
undetectable
1ru9L-2q01A:
undetectable		 1ru9H-2q01A:
19.34
1ru9L-2q01A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 6 TRP A  98
ASN A 135
LEU A 131
PHE A 121
 None
 1.47A 1rukH-2q01A:
undetectable
1rukL-2q01A:
undetectable		 1rukH-2q01A:
19.34
1rukL-2q01A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 LEU A  60
LEU A  81
ALA A  97
LEU A 131
PHE A 140
 None
 0.97A 1s9pB-2q01A:
undetectable		 1s9pB-2q01A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 LEU A 131
PHE A 105
ARG A  11
 None
 0.87A 1xdkB-2q01A:
undetectable		 1xdkB-2q01A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 ARG A  20
VAL A 429
GLY A 393
 None
 0.60A 2avvE-2q01A:
undetectable		 2avvE-2q01A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 THR A  19
PRO A  17
PRO A  14
 None
 0.82A 2d55C-2q01A:
undetectable		 2d55C-2q01A:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 HIS A  41
ASP A 329
GLY A 251
HIS A  39
ASP A 416
 None
 0.97A 2pgrA-2q01A:
2.5		 2pgrA-2q01A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 PHE A 121
ASN A 118
PHE A 130
 None
 0.89A 2zbuD-2q01A:
undetectable		 2zbuD-2q01A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 PHE A 285
PHE A 203
ALA A 211
PHE A 212
TYR A 229
 None
 1.36A 3apwB-2q01A:
undetectable		 3apwB-2q01A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 7 SER A 248
HIS A 250
LEU A 290
TRP A 226
 None
 1.21A 3arrA-2q01A:
4.8		 3arrA-2q01A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 THR A 410
GLY A 382
ASN A 414
GLY A 374
THR A 402
 None
 1.07A 3eeyA-2q01A:
undetectable		 3eeyA-2q01A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 THR A 410
GLY A 382
ASN A 414
GLY A 374
THR A 402
 None
 1.09A 3eeyB-2q01A:
undetectable		 3eeyB-2q01A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 THR A 410
GLY A 382
ASN A 414
GLY A 374
THR A 402
 None
 1.09A 3eeyH-2q01A:
undetectable		 3eeyH-2q01A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 7 PHE A 108
PHE A 101
SER A 113
TYR A  66
 None
 1.24A 3hggA-2q01A:
undetectable		 3hggA-2q01A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 428
LEU A 459
LEU A 438
SER A 435
PHE A 437
 None
 1.24A 3ko0M-2q01A:
undetectable
3ko0N-2q01A:
undetectable
3ko0O-2q01A:
undetectable
3ko0P-2q01A:
undetectable		 3ko0M-2q01A:
12.74
3ko0N-2q01A:
12.74
3ko0O-2q01A:
12.74
3ko0P-2q01A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 6 PHE A 397
TYR A 365
HIS A 388
THR A 359
 None
 1.29A 3lb3A-2q01A:
undetectable		 3lb3A-2q01A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 7 THR A 169
ASP A 249
HIS A 307
HIS A  39
 None
 0.93A 3t01A-2q01A:
undetectable		 3t01A-2q01A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 LEU A 319
GLY A 327
TYR A  66
ASN A 313
LEU A 360
 None
 1.20A 3tm4A-2q01A:
undetectable		 3tm4A-2q01A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 LEU A 319
GLY A 327
TYR A  66
ASN A 313
LEU A 360
 None
 1.20A 3tm4B-2q01A:
undetectable		 3tm4B-2q01A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 ARG A 432
PHE A  13
PRO A  14
 None
 0.44A 3zoaB-2q01A:
undetectable		 3zoaB-2q01A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 7 HIS A 307
ASP A 198
HIS A  41
HIS A 252
 None
 1.37A 3zodA-2q01A:
undetectable		 3zodA-2q01A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 7 TYR A  66
ARG A 196
HIS A  39
HIS A  65
 None
 1.15A 3zodA-2q01A:
undetectable		 3zodA-2q01A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 10 GLU A 170
VAL A 191
ALA A  48
ALA A 181
ILE A 182
 None
 1.03A 4lbgA-2q01A:
undetectable		 4lbgA-2q01A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 9 GLU A 170
VAL A 191
ALA A  48
ALA A 181
ILE A 182
 None
 1.03A 4lbgB-2q01A:
2.2		 4lbgB-2q01A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 VAL A 115
ALA A 425
PHE A   7
 None
 0.93A 4olbA-2q01A:
undetectable		 4olbA-2q01A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 VAL A 115
ALA A 425
PHE A   7
 None
 0.90A 4w5nA-2q01A:
undetectable		 4w5nA-2q01A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 11 LEU A 268
LEU A 260
GLU A 280
LYS A 281
LEU A 284
 None
 1.12A 4wg0B-2q01A:
undetectable
4wg0C-2q01A:
undetectable
4wg0D-2q01A:
undetectable		 4wg0B-2q01A:
2.11
4wg0C-2q01A:
2.11
4wg0D-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 7 LYS A 281
LEU A 284
LEU A 268
LEU A 260
 None
 0.80A 4wg0B-2q01A:
undetectable
4wg0C-2q01A:
undetectable		 4wg0B-2q01A:
2.11
4wg0C-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 11 LEU A 268
LEU A 260
GLU A 280
LYS A 281
LEU A 284
 None
 1.12A 4wg0D-2q01A:
undetectable
4wg0E-2q01A:
undetectable
4wg0F-2q01A:
undetectable		 4wg0D-2q01A:
2.11
4wg0E-2q01A:
2.11
4wg0F-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 11 GLU A 280
LYS A 281
LEU A 284
LEU A 268
LEU A 260
 None
 0.99A 4wg0C-2q01A:
undetectable
4wg0D-2q01A:
undetectable
4wg0E-2q01A:
undetectable		 4wg0C-2q01A:
2.11
4wg0D-2q01A:
2.11
4wg0E-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 11 LEU A 268
LEU A 260
GLU A 280
LYS A 281
LEU A 284
 None
 1.04A 4wg0F-2q01A:
undetectable
4wg0G-2q01A:
undetectable
4wg0H-2q01A:
undetectable		 4wg0F-2q01A:
2.11
4wg0G-2q01A:
2.11
4wg0H-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 11 GLU A 280
LYS A 281
LEU A 284
LEU A 268
LEU A 260
 None
 0.99A 4wg0E-2q01A:
undetectable
4wg0F-2q01A:
undetectable
4wg0G-2q01A:
undetectable		 4wg0E-2q01A:
2.11
4wg0F-2q01A:
2.11
4wg0G-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 11 GLU A 280
LYS A 281
LEU A 284
LEU A 268
LEU A 260
 None
 0.90A 4wg0G-2q01A:
undetectable
4wg0H-2q01A:
undetectable
4wg0I-2q01A:
undetectable		 4wg0G-2q01A:
2.11
4wg0H-2q01A:
2.11
4wg0I-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 7 LEU A 268
LEU A 260
GLU A 280
LYS A 281
LEU A 284
 None
 1.00A 4wg0L-2q01A:
undetectable
4wg0M-2q01A:
undetectable		 4wg0L-2q01A:
2.11
4wg0M-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 11 GLU A 280
LYS A 281
LEU A 284
LEU A 268
LEU A 260
 None
 0.70A 4wg0K-2q01A:
undetectable
4wg0L-2q01A:
undetectable
4wg0M-2q01A:
undetectable		 4wg0K-2q01A:
2.11
4wg0L-2q01A:
2.11
4wg0M-2q01A:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 PHE A 121
PHE A 108
LEU A 117
LEU A  81
VAL A  76
 None
 1.07A 4wnwB-2q01A:
0.7		 4wnwB-2q01A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 LEU A 421
LEU A  59
GLU A 129
LEU A 157
PHE A 152
 None
 0.88A 4y0sA-2q01A:
undetectable		 4y0sA-2q01A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 THR A 149
ASP A 150
ALA A 151
 None
 0.11A 5g5gB-2q01A:
undetectable		 5g5gB-2q01A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 12 LYS A 380
GLY A 412
GLY A 382
ASP A 415
ALA A 467
 None
 1.07A 5kpcB-2q01A:
undetectable		 5kpcB-2q01A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OWR_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		5 / 8 ALA A  56
ILE A 143
LEU A 131
ASP A 138
VAL A  76
 None
 1.21A 5owrA-2q01A:
undetectable		 5owrA-2q01A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 5 ASP A 338
PRO A 308
ARG A 333
THR A 334
 None
 1.33A 5uxcA-2q01A:
1.3		 5uxcA-2q01A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 6 PHE A 101
PHE A 140
ILE A 143
THR A 144
 None
 1.04A 5vceA-2q01A:
undetectable		 5vceA-2q01A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 5 HIS A 307
ASP A 249
HIS A  39
ARG A 196
 None
 1.43A 6dchA-2q01A:
undetectable		 6dchA-2q01A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		3 / 3 LEU A 438
LEU A 459
ARG A 398
 None
 0.70A 6fgcA-2q01A:
undetectable		 6fgcA-2q01A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 2q01 URONATE ISOMERASE
(Caulobacter
vibrioides) 		4 / 5 ASN A 414
GLY A 309
HIS A 307
ASP A 249
 None
 0.98A 6gh9A-2q01A:
undetectable		 6gh9A-2q01A:
10.27