SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 2q05 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
(Vaccinia
virus) 		3 / 3 TYR A  -4
GLY A  -1
PHE A  -3
 None
 0.62A 2m2pB-2q05A:
undetectable		 2m2pB-2q05A:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2q05 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
(Vaccinia
virus) 		3 / 3 ASP A  79
LEU A  36
ARG A 149
 None
 0.87A 5e8qA-2q05A:
undetectable		 5e8qA-2q05A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q05 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
(Vaccinia
virus) 		4 / 5 ILE A 162
PHE A  89
ARG A 116
THR A  83
 None
 1.18A 5z84N-2q05A:
undetectable
5z84W-2q05A:
undetectable		 5z84N-2q05A:
15.74
5z84W-2q05A:
16.15