SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 5 THR A 350
THR A 267
HIS A 278
LEU A 377
 None
 1.33A 1d4fC-2q07A:
undetectable		 1d4fC-2q07A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 333
GLY A 352
TYR A 370
VAL A 349
ALA A 347
 None
 1.09A 1tlsA-2q07A:
undetectable		 1tlsA-2q07A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 499
ALA A 452
ASN A 458
ILE A 520
THR A 461
 None
 1.15A 2bjfA-2q07A:
undetectable		 2bjfA-2q07A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 333
GLY A 352
TYR A 370
VAL A 349
ALA A 347
 None
 1.07A 2kceA-2q07A:
undetectable		 2kceA-2q07A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 333
GLY A 352
TYR A 370
VAL A 349
ALA A 347
 None
 1.05A 2kceB-2q07A:
undetectable		 2kceB-2q07A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA504_0
(CHORISMATE SYNTHASE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 5 SER A 381
HIS A 348
LEU A 377
SER A 378
 None
 1.18A 2qhfA-2q07A:
0.0		 2qhfA-2q07A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 499
ALA A 452
ASN A 458
ILE A 520
THR A 461
 None
 1.12A 2rlcA-2q07A:
undetectable		 2rlcA-2q07A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 336
GLY A 340
PRO A 301
ASN A 290
VAL A 345
 None
 1.04A 3av6A-2q07A:
undetectable		 3av6A-2q07A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 5 THR A 350
THR A 267
HIS A 278
LEU A 281
 None
 1.33A 3ce6A-2q07A:
2.1		 3ce6A-2q07A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 5 THR A 350
THR A 267
HIS A 278
LEU A 281
 None
 1.34A 3ce6C-2q07A:
undetectable		 3ce6C-2q07A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		3 / 3 TYR A 254
GLU A 305
TYR A 272
 None
 0.90A 3ug8A-2q07A:
undetectable		 3ug8A-2q07A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 8 ILE A 464
GLY A 465
PHE A 467
VAL A 522
 None
 0.92A 4acbB-2q07A:
2.5
4acbC-2q07A:
2.6		 4acbB-2q07A:
20.74
4acbC-2q07A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 8 ARG A 433
GLU A 426
GLU A 424
ARG A 439
 None
 1.19A 4bqfB-2q07A:
3.2		 4bqfB-2q07A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 6 LYS A 334
ILE A 337
VAL A 345
LEU A 263
 None
 0.80A 4em2A-2q07A:
undetectable		 4em2A-2q07A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 7 THR A 277
LEU A 281
LEU A 264
THR A 350
 None
 0.90A 4z90A-2q07A:
undetectable
4z90B-2q07A:
undetectable
4z90C-2q07A:
undetectable
4z90D-2q07A:
undetectable
4z90E-2q07A:
undetectable		 4z90A-2q07A:
21.49
4z90B-2q07A:
21.49
4z90C-2q07A:
21.49
4z90D-2q07A:
21.49
4z90E-2q07A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 9 TYR A 254
GLY A 340
GLY A 341
ASP A 259
ASN A 290
 None
 1.34A 5f8yA-2q07A:
undetectable		 5f8yA-2q07A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 9 TYR A 254
GLY A 340
GLY A 341
ASP A 259
ASN A 290
 None
 1.36A 5f8yB-2q07A:
undetectable		 5f8yB-2q07A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 246
SER A 275
LEU A 262
PHE A 247
ILE A 401
 None
 1.17A 5vc0A-2q07A:
undetectable		 5vc0A-2q07A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 5 THR A 350
THR A 267
HIS A 278
LEU A 377
 None
 1.35A 6aphA-2q07A:
undetectable		 6aphA-2q07A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 2q07 UNCHARACTERIZED
PROTEIN AF0587
(Archaeoglobus
fulgidus) 		4 / 5 THR A 350
THR A 267
HIS A 278
LEU A 377
 None
 1.36A 6gbnB-2q07A:
undetectable		 6gbnB-2q07A:
21.86