SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2q0v UBIQUITIN-CONJUGATIN
G ENZYME E2,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 TYR A  74
THR A  60
THR A  95
 None
 0.69A 5aoxB-2q0vA:
undetectable		 5aoxB-2q0vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2q0v UBIQUITIN-CONJUGATIN
G ENZYME E2,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 TYR A  74
THR A  60
THR A  95
 None
 0.76A 5aoxE-2q0vA:
undetectable		 5aoxE-2q0vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2q0v UBIQUITIN-CONJUGATIN
G ENZYME E2,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 ASP A  86
ASN A 120
PHE A  24
 None
 0.82A 5jglB-2q0vA:
undetectable		 5jglB-2q0vA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2q0v UBIQUITIN-CONJUGATIN
G ENZYME E2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 8 TYR A  84
THR A  90
TRP A 119
LEU A 116
 None
 1.16A 5kxiA-2q0vA:
undetectable
5kxiB-2q0vA:
undetectable		 5kxiA-2q0vA:
20.79
5kxiB-2q0vA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2q0v UBIQUITIN-CONJUGATIN
G ENZYME E2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 8 TYR A  84
THR A  90
TRP A 119
LEU A 116
 None
 1.20A 5kxiD-2q0vA:
undetectable
5kxiE-2q0vA:
undetectable		 5kxiD-2q0vA:
20.79
5kxiE-2q0vA:
15.84