SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 2q0z PROTEIN PRO2281
(Homo
sapiens) 		4 / 8 TYR X 207
PHE X 203
ARG X 236
ALA X 305
 None
 1.13A 1x8vA-2q0zX:
undetectable		 1x8vA-2q0zX:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2q0z PROTEIN PRO2281
(Homo
sapiens) 		3 / 3 HIS X  81
ILE X 108
LEU X 115
 None
 0.74A 2kceA-2q0zX:
undetectable		 2kceA-2q0zX:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 2q0z PROTEIN PRO2281
(Homo
sapiens) 		4 / 4 LEU X  92
ARG X 253
LEU X 109
ALA X 139
 None
 0.97A 3b9mA-2q0zX:
undetectable		 3b9mA-2q0zX:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 2q0z PROTEIN PRO2281
(Homo
sapiens) 		5 / 12 GLU X 211
LEU X 277
ARG X 236
GLU X 237
GLU X 238
 None
 1.45A 4cpzD-2q0zX:
undetectable		 4cpzD-2q0zX:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 2q0z PROTEIN PRO2281
(Homo
sapiens) 		5 / 12 GLU X 211
LEU X 277
ARG X 236
GLU X 237
GLU X 238
 None
 1.44A 4cpzE-2q0zX:
undetectable		 4cpzE-2q0zX:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 2q0z PROTEIN PRO2281
(Homo
sapiens) 		5 / 12 MET X 141
GLN X 140
ILE X 113
VAL X 120
CYH X 119
 None
 1.33A 5vlmB-2q0zX:
undetectable		 5vlmB-2q0zX:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2q0z PROTEIN PRO2281
(Homo
sapiens) 		4 / 5 LEU X  64
LYS X  83
LEU X  60
GLU X  57
 None
 1.35A 5weaA-2q0zX:
undetectable		 5weaA-2q0zX:
17.04