SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 793
ALA A 806
VAL A 803
 None
 0.95A 1c4dA-2q1fA:
undetectable
1c4dB-2q1fA:
undetectable		 1c4dA-2q1fA:
2.16
1c4dB-2q1fA:
2.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 883
GLU A 881
GLU A 847
MET A 748
 None
None
None
PO4  A2005 (-3.6A)
 1.09A 1dtlA-2q1fA:
undetectable		 1dtlA-2q1fA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 681
PRO A 682
LEU A 685
 None
 0.53A 1hrkA-2q1fA:
undetectable		 1hrkA-2q1fA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR A 630
GLY A 698
VAL A 693
ASP A 694
HIS A 454
 None
 1.30A 1kiaD-2q1fA:
undetectable		 1kiaD-2q1fA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PHE A 668
LEU A 509
LEU A 640
 None
 0.63A 1mx1E-2q1fA:
undetectable		 1mx1E-2q1fA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR A 630
GLY A 698
VAL A 693
ASP A 694
HIS A 454
 None
 1.29A 1nbhC-2q1fA:
undetectable		 1nbhC-2q1fA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_2
(NEURAMINIDASE N9)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 177
ARG A 126
TRP A 340
ILE A 343
 None
 1.49A 1nncA-2q1fA:
undetectable		 1nncA-2q1fA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 163
PHE A  25
LEU A  67
SER A  39
 None
 1.01A 1wrlE-2q1fA:
undetectable
1wrlF-2q1fA:
undetectable		 1wrlE-2q1fA:
6.67
1wrlF-2q1fA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 783
THR A 799
TYR A 801
 None
 1.06A 2a3aA-2q1fA:
undetectable		 2a3aA-2q1fA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 783
THR A 799
TYR A 801
 None
 1.04A 2a3aB-2q1fA:
undetectable		 2a3aB-2q1fA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_A_ADNA1001_1
(CLASS B ACID
PHOSPHATASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		5 / 10 PHE A 770
GLU A 810
TRP A 783
GLY A 788
THR A 768
 None
 1.16A 2b82A-2q1fA:
0.0		 2b82A-2q1fA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 853
PRO A 852
ILE A 850
GLY A 800
 None
 0.86A 2jklB-2q1fA:
undetectable		 2jklB-2q1fA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 640
ARG A 514
PRO A 658
GLY A 520
 None
 0.68A 2po5A-2q1fA:
undetectable		 2po5A-2q1fA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 640
ARG A 514
PRO A 658
GLY A 520
 None
 0.71A 2po5B-2q1fA:
undetectable		 2po5B-2q1fA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLN A 174
ALA A 268
ALA A 271
THR A 167
 None
 1.03A 2xfhA-2q1fA:
undetectable		 2xfhA-2q1fA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 965
GLY A 603
GLY A 450
LYS A 446
 None
 0.97A 2y4nB-2q1fA:
undetectable		 2y4nB-2q1fA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 846
SER A 832
GLN A 771
ASP A 836
 None
 1.38A 2zvjA-2q1fA:
undetectable		 2zvjA-2q1fA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A1007
GLY A 712
GLY A 720
 None
 0.57A 3bogA-2q1fA:
undetectable
3bogC-2q1fA:
undetectable		 3bogA-2q1fA:
undetectable
3bogC-2q1fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 529
THR A 404
PHE A 427
PHE A 476
 None
 1.05A 3em0A-2q1fA:
3.5		 3em0A-2q1fA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 640
ARG A 514
PRO A 658
GLY A 520
 None
 0.99A 3hcrB-2q1fA:
undetectable		 3hcrB-2q1fA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 424
SER A 426
PHE A 427
ILE A 411
 None
 1.03A 3ko0S-2q1fA:
undetectable		 3ko0S-2q1fA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 194
LEU A 353
ARG A 378
ILE A 382
 None
None
PO4  A2002 (-2.5A)
None
 0.87A 3ln1A-2q1fA:
undetectable		 3ln1A-2q1fA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 194
LEU A 353
ARG A 378
ILE A 382
 None
None
PO4  A2002 (-2.5A)
None
 0.88A 3ln1B-2q1fA:
undetectable		 3ln1B-2q1fA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 VAL A 792
TYR A 848
TYR A 801
LEU A 851
GLU A 847
 None
 1.43A 3m8pA-2q1fA:
1.3
3m8pB-2q1fA:
0.3		 3m8pA-2q1fA:
19.54
3m8pB-2q1fA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 295
ILE A 329
ALA A 373
THR A 376
 None
 1.00A 3mdrB-2q1fA:
undetectable		 3mdrB-2q1fA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ALA A 531
ILE A 579
LEU A 583
ALA A 549
 None
 0.86A 3r9sA-2q1fA:
undetectable		 3r9sA-2q1fA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 194
ASP A 177
ALA A 176
TYR A 346
 None
 1.16A 3rodD-2q1fA:
undetectable		 3rodD-2q1fA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A 177
ARG A 126
TRP A 340
ILE A 343
 None
 1.49A 3sanB-2q1fA:
undetectable		 3sanB-2q1fA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 425
SER A 210
GLN A 213
 None
 0.93A 3si7A-2q1fA:
undetectable		 3si7A-2q1fA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 602
LEU A 726
LYS A 725
 None
 0.66A 3sueD-2q1fA:
undetectable		 3sueD-2q1fA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 768
VAL A 676
GLU A 766
 None
 0.44A 3v4tA-2q1fA:
undetectable
3v4tD-2q1fA:
undetectable		 3v4tA-2q1fA:
18.45
3v4tD-2q1fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 367
GLY A 368
TYR A 326
GLU A 372
 None
 1.45A 3w9tA-2q1fA:
undetectable		 3w9tA-2q1fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 327
GLU A 367
LEU A 323
TYR A 326
 None
 1.04A 3w9tB-2q1fA:
undetectable		 3w9tB-2q1fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 367
GLY A 368
TYR A 326
GLU A 372
 None
 1.45A 3w9tC-2q1fA:
undetectable		 3w9tC-2q1fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 367
GLY A 368
TYR A 326
GLU A 372
 None
 1.45A 3w9tD-2q1fA:
undetectable		 3w9tD-2q1fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 327
GLU A 367
LEU A 323
TYR A 326
 None
 1.04A 3w9tE-2q1fA:
undetectable		 3w9tE-2q1fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 327
GLU A 367
LEU A 323
TYR A 326
 None
 1.02A 3w9tF-2q1fA:
undetectable		 3w9tF-2q1fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 367
GLY A 368
TYR A 326
GLU A 372
 None
 1.44A 3w9tG-2q1fA:
undetectable		 3w9tG-2q1fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 573
GLU A 576
ARG A 577
 None
 0.96A 3wxoA-2q1fA:
undetectable		 3wxoA-2q1fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 194
GLU A 385
SER A 198
 None
 0.67A 4ccqA-2q1fA:
undetectable		 4ccqA-2q1fA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 270
HIS A 344
VAL A 169
GLU A 273
 None
 1.05A 4hvrA-2q1fA:
undetectable		 4hvrA-2q1fA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLU A 415
GLU A 221
ILE A 411
LEU A 220
 None
 0.94A 4mj8A-2q1fA:
undetectable		 4mj8A-2q1fA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 503
ASP A 593
ASP A 557
 None
 0.79A 4obwD-2q1fA:
undetectable		 4obwD-2q1fA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 406
PHE A 427
ILE A 411
PHE A 476
 None
 0.94A 4qogA-2q1fA:
undetectable
4qogB-2q1fA:
undetectable		 4qogA-2q1fA:
12.54
4qogB-2q1fA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 725
ARG A 737
HIS A 727
 None
 1.20A 4zbrA-2q1fA:
1.7		 4zbrA-2q1fA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 908
THR A 895
PHE A 893
 None
 0.91A 5cxvA-2q1fA:
undetectable		 5cxvA-2q1fA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 910
THR A 895
PHE A 893
 None
 0.55A 5cxvA-2q1fA:
undetectable		 5cxvA-2q1fA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLU A 545
PRO A 536
GLY A 540
ASP A 537
 None
 1.02A 5kgpA-2q1fA:
undetectable		 5kgpA-2q1fA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLU A 545
PRO A 536
GLY A 540
ASP A 537
 None
 1.00A 5kgpB-2q1fA:
undetectable		 5kgpB-2q1fA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M67_B_ACTB505_0
(ADENOSYLHOMOCYSTEINA
SE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 836
ILE A 834
ARG A 672
ARG A 808
 None
 1.02A 5m67B-2q1fA:
0.0		 5m67B-2q1fA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 573
VAL A 463
HIS A 526
 None
 0.78A 6a5yD-2q1fA:
undetectable		 6a5yD-2q1fA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 453
HIS A 454
ARG A 514
 None
 0.85A 6b58A-2q1fA:
3.2		 6b58A-2q1fA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 489
LYS A 492
ARG A 582
 None
 1.34A 6c06D-2q1fA:
undetectable		 6c06D-2q1fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL A 676
SER A 678
LEU A 686
GLY A 619
GLY A 637
 None
 0.89A 6eu9B-2q1fA:
undetectable		 6eu9B-2q1fA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ARG A 808
GLU A 810
GLU A 766
ARG A 672
 None
 0.95A 6fk2A-2q1fA:
5.2		 6fk2A-2q1fA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 2q1f CHONDROITINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 ILE A 749
LEU A 880
ASP A 885
ASN A 719
ALA A 867
 None
None
PO4  A2005 (-3.4A)
None
PO4  A2005 ( 4.0A)
 1.37A 6r2eF-2q1fA:
undetectable		 6r2eF-2q1fA:
16.33