SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q24 PUTATIVE TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		4 / 7 ILE A 146
ARG A 151
MET A 155
LEU A 133
 None
 1.00A 2dyrN-2q24A:
undetectable
2dyrW-2q24A:
undetectable		 2dyrN-2q24A:
17.09
2dyrW-2q24A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q24 PUTATIVE TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		4 / 6 ILE A 146
ARG A 151
MET A 155
LEU A 133
 None
 0.97A 2einN-2q24A:
undetectable
2einW-2q24A:
undetectable		 2einN-2q24A:
17.09
2einW-2q24A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q24 PUTATIVE TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		4 / 7 ILE A 146
ARG A 151
MET A 155
LEU A 133
 None
 1.01A 3ablA-2q24A:
undetectable
3ablJ-2q24A:
undetectable		 3ablA-2q24A:
17.09
3ablJ-2q24A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2q24 PUTATIVE TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		3 / 3 PHE A  97
ASP A  99
LEU A  84
 None
 0.77A 5uhbC-2q24A:
undetectable		 5uhbC-2q24A:
10.53