SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2q2b CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Mus
musculus) 		5 / 10 GLY A 252
ALA A 286
VAL A 266
GLU A 265
VAL A 215
 None
 1.13A 4da7A-2q2bA:
undetectable		 4da7A-2q2bA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 2q2b CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Mus
musculus) 		5 / 12 ALA A 283
ASP A 269
ILE A 248
ILE A 250
ILE A 242
 None
 0.88A 4q1xB-2q2bA:
undetectable		 4q1xB-2q2bA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2q2b CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Mus
musculus) 		4 / 7 VAL A 233
ILE A 236
VAL A 266
ALA A 286
 None
 0.71A 5ospA-2q2bA:
undetectable		 5ospA-2q2bA:
20.54