SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 2q2i SECRETION CHAPERONE
(Agrobacterium
fabrum) 		5 / 11 LEU A  62
VAL A  21
ILE A  46
ALA A  23
ILE A  20
 None
 0.94A 2idwA-2q2iA:
undetectable		 2idwA-2q2iA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 2q2i SECRETION CHAPERONE
(Agrobacterium
fabrum) 		5 / 9 LEU A  62
VAL A  21
ILE A  46
ALA A  23
ILE A  20
 None
 0.98A 3el0B-2q2iA:
undetectable		 3el0B-2q2iA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2q2i SECRETION CHAPERONE
(Agrobacterium
fabrum) 		5 / 12 GLY A  18
GLY A 109
VAL A  67
ASP A  39
ILE A  38
 None
 0.92A 4ctjC-2q2iA:
undetectable		 4ctjC-2q2iA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2q2i SECRETION CHAPERONE
(Agrobacterium
fabrum) 		5 / 12 ALA A  51
GLY A  89
GLY A  69
LEU A  68
ALA A  91
 None
 1.19A 5c0oE-2q2iA:
undetectable		 5c0oE-2q2iA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2q2i SECRETION CHAPERONE
(Agrobacterium
fabrum) 		4 / 6 SER A  83
GLY A  41
ARG A  16
GLY A  18
 None
 0.87A 5cdnC-2q2iA:
undetectable
5cdnD-2q2iA:
undetectable		 5cdnC-2q2iA:
14.96
5cdnD-2q2iA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2q2i SECRETION CHAPERONE
(Agrobacterium
fabrum) 		5 / 12 GLY A  18
GLY A 109
VAL A  67
ASP A  39
ILE A  38
 None
 0.92A 5ehgC-2q2iA:
undetectable		 5ehgC-2q2iA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 2q2i SECRETION CHAPERONE
(Agrobacterium
fabrum) 		5 / 12 GLY A  18
GLY A 109
VAL A  67
ASP A  39
ILE A  38
 None
 0.90A 5ekxB-2q2iA:
undetectable		 5ekxB-2q2iA:
18.48