SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q34'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2q34 CURF
(Moorea
producens) 		5 / 12 ALA A 151
LEU A 160
ALA A 165
LEU A 124
ILE A 155
 None
 1.05A 1g5yB-2q34A:
undetectable		 1g5yB-2q34A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 2q34 CURF
(Moorea
producens) 		5 / 10 VAL A 129
LEU A 124
LEU A 120
TYR A 137
ALA A 109
 None
 1.36A 1pbcA-2q34A:
undetectable		 1pbcA-2q34A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2q34 CURF
(Moorea
producens) 		5 / 8 LEU A 124
ILE A 155
LEU A 156
THR A 139
LEU A 120
 None
 1.25A 2xfhA-2q34A:
undetectable		 2xfhA-2q34A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 2q34 CURF
(Moorea
producens) 		5 / 12 GLN A 133
GLY A  69
SER A 115
LEU A  67
ALA A 109
 None
 1.23A 3d91A-2q34A:
undetectable		 3d91A-2q34A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2q34 CURF
(Moorea
producens) 		4 / 8 VAL A  64
CYH A 103
VAL A  28
ILE A 107
 None
 1.05A 4aftD-2q34A:
undetectable
4aftE-2q34A:
undetectable		 4aftD-2q34A:
24.44
4aftE-2q34A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2q34 CURF
(Moorea
producens) 		4 / 8 PHE A  74
VAL A  18
SER A  75
GLY A  69
 None
 0.81A 4m48A-2q34A:
undetectable		 4m48A-2q34A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2q34 CURF
(Moorea
producens) 		5 / 12 LEU A 122
ILE A  45
ILE A 100
ILE A  30
PHE A  53
 None
 1.19A 4rp8C-2q34A:
undetectable		 4rp8C-2q34A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2q34 CURF
(Moorea
producens) 		4 / 8 MET A 111
PHE A 131
ALA A 138
GLY A 177
 None
 1.00A 4xk8a-2q34A:
undetectable		 4xk8a-2q34A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2q34 CURF
(Moorea
producens) 		4 / 8 LEU A 101
PHE A 229
GLY A 150
THR A 152
 None
 0.69A 5eseA-2q34A:
undetectable		 5eseA-2q34A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2q34 CURF
(Moorea
producens) 		4 / 4 VAL A 130
VAL A 195
TYR A 198
GLN A 200
 None
 1.49A 5qgpA-2q34A:
undetectable		 5qgpA-2q34A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2q34 CURF
(Moorea
producens) 		4 / 4 VAL A 130
VAL A 195
TYR A 198
GLN A 200
 None
 1.48A 5qgqA-2q34A:
undetectable		 5qgqA-2q34A:
20.63