SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.86A 1jnoA-2q3hA:
undetectable		 1jnoA-2q3hA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.87A 1jnoB-2q3hA:
undetectable		 1jnoB-2q3hA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.92A 1magA-2q3hA:
undetectable		 1magA-2q3hA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.92A 1magB-2q3hA:
undetectable		 1magB-2q3hA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.88A 1ng8A-2q3hA:
undetectable		 1ng8A-2q3hA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.88A 1ng8B-2q3hA:
undetectable		 1ng8B-2q3hA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.91A 1nruA-2q3hA:
undetectable		 1nruA-2q3hA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ALA A 105
VAL A  55
TRP A 143
 None
 0.91A 1nruB-2q3hA:
undetectable		 1nruB-2q3hA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		5 / 10 ASP A 216
GLY A 222
ILE A 123
VAL A  90
VAL A  92
 None
 1.12A 3nu9B-2q3hA:
undetectable		 3nu9B-2q3hA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 ARG A 166
TYR A 200
GLU A 202
 None
 0.54A 4zzbE-2q3hA:
undetectable		 4zzbE-2q3hA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		3 / 3 TRP A 143
GLU A 146
ASP A 108
 None
 1.04A 5gqbA-2q3hA:
2.6		 5gqbA-2q3hA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 2q3h RAS HOMOLOG GENE
FAMILY, MEMBER U
(Homo
sapiens) 		5 / 11 VAL A  66
THR A  70
VAL A  55
ALA A  88
VAL A 214
 None
 1.13A 6dryA-2q3hA:
undetectable		 6dryA-2q3hA:
18.50