SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 12 ALA A 213
GLY A 209
TYR A 208
LEU A 219
GLN A 221
 None
 1.28A 1brpA-2q3oA:
undetectable		 1brpA-2q3oA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 6 VAL A 261
GLY A 262
ALA A 312
LEU A 309
 None
 0.78A 1e7bB-2q3oA:
undetectable		 1e7bB-2q3oA:
19.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H60_A_STRA500_1
(PENTAERYTHRITOL
TETRANITRATE
REDUCTASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 9 THR A  33
HIS A 186
HIS A 189
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 (-3.3A)
FMN  A7401 (-4.4A)
None
FMN  A7401 (-4.0A)
 0.48A 1h60A-2q3oA:
51.9		 1h60A-2q3oA:
38.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		3 / 3 ALA A  44
VAL A  92
TRP A  89
 None
 0.85A 1micA-2q3oA:
undetectable
1micB-2q3oA:
undetectable		 1micA-2q3oA:
5.17
1micB-2q3oA:
5.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 12 ALA A 213
GLY A 209
TYR A 208
LEU A 219
GLN A 221
 None
 1.22A 1qabF-2q3oA:
undetectable		 1qabF-2q3oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 12 VAL A 165
ILE A 176
ILE A 193
ILE A 185
VAL A 235
 None
 1.32A 1r5lA-2q3oA:
undetectable		 1r5lA-2q3oA:
21.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ABA_A_STRA1500_1
(PENTAERYTHRITOL
TETRANITRATE
REDUCTASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 9 THR A  33
HIS A 186
HIS A 189
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 (-3.3A)
FMN  A7401 (-4.4A)
None
FMN  A7401 (-4.0A)
 0.52A 2abaA-2q3oA:
52.1		 2abaA-2q3oA:
38.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		3 / 3 ASP A 338
VAL A  28
PRO A  31
 None
None
FMN  A7401 (-4.3A)
 0.73A 2avvA-2q3oA:
undetectable		 2avvA-2q3oA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 12 HIS A 189
ASP A 194
GLY A 187
HIS A 186
GLU A 184
 FMN  A7401 (-4.4A)
None
None
FMN  A7401 (-3.3A)
None
 1.22A 2pgfA-2q3oA:
7.3		 2pgfA-2q3oA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		6 / 10 LEU A 173
ASP A 181
GLY A 236
ILE A 185
ALA A 229
ILE A 230
 None
 1.48A 3ekpB-2q3oA:
undetectable		 3ekpB-2q3oA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		6 / 10 LEU A 173
ASP A 181
GLY A 236
ILE A 185
ALA A 229
ILE A 230
 None
 1.48A 3ekpC-2q3oA:
undetectable		 3ekpC-2q3oA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 12 PHE A 317
MET A 306
LEU A 305
GLY A 257
LEU A 264
 None
 1.20A 3i5uA-2q3oA:
undetectable		 3i5uA-2q3oA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 8 ASP A 338
GLY A 236
ILE A 185
PRO A  31
 None
None
None
FMN  A7401 (-4.3A)
 0.75A 3nu9A-2q3oA:
undetectable		 3nu9A-2q3oA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 7 ILE A 133
LEU A 246
VAL A  67
SER A  68
 None
 0.94A 3r9vA-2q3oA:
undetectable
3r9vB-2q3oA:
undetectable		 3r9vA-2q3oA:
20.70
3r9vB-2q3oA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 7 VAL A 237
MET A 263
LEU A 197
ILE A 193
 None
 1.01A 3rfmA-2q3oA:
undetectable		 3rfmA-2q3oA:
20.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPW_A_NCAA412_0
(OLD YELLOW ENZYME
2.6 (OYE2.6), NADPH
DEHYDROGENASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 9 THR A  33
HIS A 186
HIS A 189
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 (-3.3A)
FMN  A7401 (-4.4A)
None
FMN  A7401 (-4.0A)
 0.53A 3upwA-2q3oA:
46.9		 3upwA-2q3oA:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A3U_A_ACTA1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 9 ALA A  30
PRO A  31
ILE A  61
ARG A 238
SER A 341
 FMN  A7401 (-3.6A)
FMN  A7401 (-4.3A)
None
FMN  A7401 (-3.7A)
None
 0.46A 4a3uA-2q3oA:
52.2		 4a3uA-2q3oA:
39.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 7 THR A  33
TRP A 108
HIS A 186
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 ( 4.6A)
FMN  A7401 (-3.3A)
None
FMN  A7401 (-4.0A)
 0.42A 4a3uA-2q3oA:
52.2		 4a3uA-2q3oA:
39.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 7 PRO A  31
ILE A  61
ARG A 238
SER A 341
 FMN  A7401 (-4.3A)
None
FMN  A7401 (-3.7A)
None
 0.44A 4a3uB-2q3oA:
52.3		 4a3uB-2q3oA:
39.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 7 THR A  33
TRP A 108
HIS A 186
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 ( 4.6A)
FMN  A7401 (-3.3A)
None
FMN  A7401 (-4.0A)
 0.44A 4a3uB-2q3oA:
52.3		 4a3uB-2q3oA:
39.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 7 THR A  33
TRP A 108
HIS A 186
TYR A 191
LEU A 246
 FMN  A7401 (-3.8A)
FMN  A7401 ( 4.6A)
FMN  A7401 (-3.3A)
None
None
 1.33A 4awuA-2q3oA:
53.9		 4awuA-2q3oA:
42.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 6 THR A  33
HIS A 186
HIS A 189
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 (-3.3A)
FMN  A7401 (-4.4A)
None
FMN  A7401 (-4.0A)
 0.50A 4df2A-2q3oA:
46.8		 4df2A-2q3oA:
34.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 9 ALA A 276
GLY A 231
ILE A 176
GLY A 182
ILE A 183
 None
 1.10A 4eatB-2q3oA:
undetectable		 4eatB-2q3oA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 8 ASN A 271
LEU A 264
TYR A 313
LEU A 275
 None
 0.97A 4jjkA-2q3oA:
2.2		 4jjkA-2q3oA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 12 SER A 128
HIS A 109
GLY A 187
SER A  68
TYR A  81
 None
 1.41A 4kn2C-2q3oA:
undetectable		 4kn2C-2q3oA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		3 / 3 SER A 320
MET A 318
ASP A 194
 FMN  A7401 ( 4.2A)
None
None
 0.81A 4mm4B-2q3oA:
undetectable		 4mm4B-2q3oA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 5 ILE A  61
PRO A  31
HIS A 245
VAL A  77
 None
FMN  A7401 (-4.3A)
None
None
 1.35A 4s0vA-2q3oA:
undetectable		 4s0vA-2q3oA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 4 LEU A 278
LEU A 275
GLY A 236
GLU A 184
 None
 1.22A 5hhjA-2q3oA:
undetectable		 5hhjA-2q3oA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 12 ILE A 185
THR A  33
PHE A 104
ALA A 276
SER A 320
 None
FMN  A7401 (-3.8A)
None
None
FMN  A7401 ( 4.2A)
 1.29A 5iwuA-2q3oA:
undetectable		 5iwuA-2q3oA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 9 HIS A 189
HIS A 279
LEU A 278
THR A 281
SER A 320
 FMN  A7401 (-4.4A)
None
None
None
FMN  A7401 ( 4.2A)
 1.11A 5m8nD-2q3oA:
0.0		 5m8nD-2q3oA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 7 HIS A 189
HIS A 279
LEU A 278
SER A 320
 FMN  A7401 (-4.4A)
None
None
FMN  A7401 ( 4.2A)
 0.74A 5m8rA-2q3oA:
undetectable		 5m8rA-2q3oA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 8 HIS A 189
HIS A 279
LEU A 278
SER A 320
 FMN  A7401 (-4.4A)
None
None
FMN  A7401 ( 4.2A)
 0.74A 5m8rB-2q3oA:
undetectable		 5m8rB-2q3oA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 8 HIS A 189
HIS A 279
LEU A 278
SER A 320
 FMN  A7401 (-4.4A)
None
None
FMN  A7401 ( 4.2A)
 0.74A 5m8rD-2q3oA:
undetectable		 5m8rD-2q3oA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		3 / 3 GLU A  48
TYR A  49
ARG A  53
 None
 0.74A 5uunA-2q3oA:
undetectable		 5uunA-2q3oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		3 / 3 GLU A  48
TYR A  49
ARG A  53
 None
 0.80A 5uunB-2q3oA:
undetectable		 5uunB-2q3oA:
22.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 8 THR A  33
TRP A 108
HIS A 186
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 ( 4.6A)
FMN  A7401 (-3.3A)
None
FMN  A7401 (-4.0A)
 0.54A 5v4vA-2q3oA:
49.1		 5v4vA-2q3oA:
36.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		5 / 8 THR A  33
TRP A 108
HIS A 186
TYR A 191
TYR A 371
 FMN  A7401 (-3.8A)
FMN  A7401 ( 4.6A)
FMN  A7401 (-3.3A)
None
FMN  A7401 (-4.0A)
 0.53A 5v4vB-2q3oA:
49.1		 5v4vB-2q3oA:
36.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 6 MET A 263
GLY A 269
ALA A 232
LEU A 275
 None
 1.04A 6fosA-2q3oA:
undetectable		 6fosA-2q3oA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2q3o 12-OXOPHYTODIENOATE
REDUCTASE 3
(Arabidopsis
thaliana) 		4 / 7 ILE A 243
GLU A 184
HIS A 186
TRP A 138
 None
None
FMN  A7401 (-3.3A)
None
 1.20A 6j20A-2q3oA:
undetectable		 6j20A-2q3oA:
21.63