SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q3s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QO6_A_CHDA130_0 (LIVER-BASIC FATTY ACID BINDING PROTEIN)	2q3s	PROTEIN AT5G06450 (Arabidopsis thaliana)	5 / 12	TYR A 101 LEU A 129 ILE A 131 LEU A 123 PHE A 111	None	1.30A	2qo6A-2q3sA: undetectable	2qo6A-2q3sA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJX_B_HCZB800_1 (GLUTAMATE RECEPTOR 2)	2q3s	PROTEIN AT5G06450 (Arabidopsis thaliana)	5 / 10	PRO A 32 SER A 1 LEU A 85 ILE A 22 SER A 3	None	1.27A	3ijxB-2q3sA: undetectable 3ijxD-2q3sA: undetectable	3ijxB-2q3sA: 23.16 3ijxD-2q3sA: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJX_D_HCZD800_1 (GLUTAMATE RECEPTOR 2)	2q3s	PROTEIN AT5G06450 (Arabidopsis thaliana)	5 / 9	ILE A 22 SER A 3 PRO A 32 SER A 1 LEU A 85	None	1.30A	3ijxB-2q3sA: 0.0 3ijxD-2q3sA: 0.0	3ijxB-2q3sA: 23.16 3ijxD-2q3sA: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2q3s	PROTEIN AT5G06450 (Arabidopsis thaliana)	4 / 7	SER A 106 LEU A 87 ILE A 131 PHE A 104	None	0.99A	3ln1C-2q3sA: undetectable	3ln1C-2q3sA: 17.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QO6_A_CHDA130_0","LIVER-BASIC FATTY ACID BINDING PROTEIN","2q3s","PROTEIN AT5G06450","Arabidopsis thaliana",5,"TYR A 101;LEU A 129;ILE A 131;LEU A 123;PHE A 111","None","1.30A","2qo6A-2q3sA:undetectable","2qo6A-2q3sA:21.80"],["3IJX_B_HCZB800_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","2q3s","PROTEIN AT5G06450","Arabidopsis thaliana",5,"PRO A  32;SER A   1;LEU A  85;ILE A  22;SER A   3","None","1.27A","3ijxB-2q3sA:undetectable;3ijxD-2q3sA:undetectable","3ijxB-2q3sA:23.16;3ijxD-2q3sA:23.16"],["3IJX_D_HCZD800_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","2q3s","PROTEIN AT5G06450","Arabidopsis thaliana",5,"ILE A  22;SER A   3;PRO A  32;SER A   1;LEU A  85","None","1.30A","3ijxB-2q3sA:0.0;3ijxD-2q3sA:0.0","3ijxB-2q3sA:23.16;3ijxD-2q3sA:23.16"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2q3s","PROTEIN AT5G06450","Arabidopsis thaliana",4,"SER A 106;LEU A  87;ILE A 131;PHE A 104","None","0.99A","3ln1C-2q3sA:undetectable","3ln1C-2q3sA:17.34"]]