SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_A_HLTA4001_1 (SERUM ALBUMIN)	2q47	PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000 (Arabidopsis thaliana)	4 / 5	ARG A 188 ALA A 183 ASP A 191 GLY A 158	SO4 A 203 ( 4.2A) None None None	1.15A	1e7bA-2q47A: undetectable	1e7bA-2q47A: 13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JB7_B_ACTB1169_0 (HYPOTHETICAL PROTEIN PAE2307)	2q47	PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000 (Arabidopsis thaliana)	3 / 3	ARG A 152 ARG A 188 ARG A 156	SO4 A 204 ( 3.9A) SO4 A 203 ( 4.2A) SO4 A 203 (-3.7A)	1.12A	2jb7A-2q47A: undetectable 2jb7B-2q47A: undetectable 2jb7C-2q47A: undetectable	2jb7A-2q47A: 18.34 2jb7B-2q47A: 18.34 2jb7C-2q47A: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JB7_B_ACTB1169_0 (HYPOTHETICAL PROTEIN PAE2307)	2q47	PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000 (Arabidopsis thaliana)	3 / 3	ARG A 156 ARG A 152 ARG A 188	SO4 A 203 (-3.7A) SO4 A 204 ( 3.9A) SO4 A 203 ( 4.2A)	1.08A	2jb7A-2q47A: undetectable 2jb7B-2q47A: undetectable 2jb7C-2q47A: undetectable	2jb7A-2q47A: 18.34 2jb7B-2q47A: 18.34 2jb7C-2q47A: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JB7_B_ACTB1169_0 (HYPOTHETICAL PROTEIN PAE2307)	2q47	PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000 (Arabidopsis thaliana)	3 / 3	ARG A 188 ARG A 156 ARG A 152	SO4 A 203 ( 4.2A) SO4 A 203 (-3.7A) SO4 A 204 ( 3.9A)	1.06A	2jb7A-2q47A: undetectable 2jb7B-2q47A: undetectable 2jb7C-2q47A: undetectable	2jb7A-2q47A: 18.34 2jb7B-2q47A: 18.34 2jb7C-2q47A: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD2_A_CHDA2_0 (FERROCHELATASE)	2q47	PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000 (Arabidopsis thaliana)	4 / 8	LEU A 139 ARG A 165 SER A 87 VAL A 62	None	1.19A	2qd2A-2q47A: 3.0	2qd2A-2q47A: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VRM_A_VD3A502_1 (VITAMIN D(3) 25-HYDROXYLASE)	2q47	PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000 (Arabidopsis thaliana)	5 / 12	PRO A 72 ILE A 148 LEU A 111 LEU A 91 ALA A 134	None	1.03A	3vrmA-2q47A: undetectable	3vrmA-2q47A: 15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA504_0 (FERROCHELATASE, MITOCHONDRIAL)	2q47	PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000 (Arabidopsis thaliana)	4 / 7	LEU A 139 ARG A 165 SER A 87 VAL A 62	None	1.00A	4klrA-2q47A: undetectable	4klrA-2q47A: 18.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_A_HLTA4001_1","SERUM ALBUMIN","2q47","PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000","Arabidopsis thaliana",4,"ARG A 188;ALA A 183;ASP A 191;GLY A 158","SO4 A 203 ( 4.2A);None;None;None","1.15A","1e7bA-2q47A:undetectable","1e7bA-2q47A:13.66"],["2JB7_B_ACTB1169_0","HYPOTHETICAL PROTEIN PAE2307","2q47","PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000","Arabidopsis thaliana",3,"ARG A 152;ARG A 188;ARG A 156","SO4 A 204 ( 3.9A);SO4 A 203 ( 4.2A);SO4 A 203 (-3.7A)","1.12A","2jb7A-2q47A:undetectable;2jb7B-2q47A:undetectable;2jb7C-2q47A:undetectable","2jb7A-2q47A:18.34;2jb7B-2q47A:18.34;2jb7C-2q47A:18.34"],["2JB7_B_ACTB1169_0","HYPOTHETICAL PROTEIN PAE2307","2q47","PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000","Arabidopsis thaliana",3,"ARG A 156;ARG A 152;ARG A 188","SO4 A 203 (-3.7A);SO4 A 204 ( 3.9A);SO4 A 203 ( 4.2A)","1.08A","2jb7A-2q47A:undetectable;2jb7B-2q47A:undetectable;2jb7C-2q47A:undetectable","2jb7A-2q47A:18.34;2jb7B-2q47A:18.34;2jb7C-2q47A:18.34"],["2JB7_B_ACTB1169_0","HYPOTHETICAL PROTEIN PAE2307","2q47","PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000","Arabidopsis thaliana",3,"ARG A 188;ARG A 156;ARG A 152","SO4 A 203 ( 4.2A);SO4 A 203 (-3.7A);SO4 A 204 ( 3.9A)","1.06A","2jb7A-2q47A:undetectable;2jb7B-2q47A:undetectable;2jb7C-2q47A:undetectable","2jb7A-2q47A:18.34;2jb7B-2q47A:18.34;2jb7C-2q47A:18.34"],["2QD2_A_CHDA2_0","FERROCHELATASE","2q47","PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000","Arabidopsis thaliana",4,"LEU A 139;ARG A 165;SER A  87;VAL A  62","None","1.19A","2qd2A-2q47A:3.0","2qd2A-2q47A:18.84"],["3VRM_A_VD3A502_1","VITAMIN D(3) 25-HYDROXYLASE","2q47","PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000","Arabidopsis thaliana",5,"PRO A  72;ILE A 148;LEU A 111;LEU A  91;ALA A 134","None","1.03A","3vrmA-2q47A:undetectable","3vrmA-2q47A:15.17"],["4KLR_A_CHDA504_0","FERROCHELATASE, MITOCHONDRIAL","2q47","PROBABLE TYROSINE-PROTEIN PHOSPHATASE AT1G05000","Arabidopsis thaliana",4,"LEU A 139;ARG A 165;SER A  87;VAL A  62","None","1.00A","4klrA-2q47A:undetectable","4klrA-2q47A:18.66"]]