SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q4d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		5 / 12 LEU A 112
LEU A  53
LEU A  37
CYH A  13
PHE A  15
 None
 1.46A 1a28A-2q4dA:
undetectable		 1a28A-2q4dA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		4 / 4 ASP A 155
LEU A 150
LEU A 153
LEU A 151
 None
 1.40A 1u18A-2q4dA:
undetectable		 1u18A-2q4dA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		3 / 3 LEU A 112
PRO A 113
LEU A  53
 None
 0.41A 2po5B-2q4dA:
3.3		 2po5B-2q4dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		3 / 3 LEU A 112
PRO A 113
LEU A  53
 None
 0.36A 2po7B-2q4dA:
undetectable		 2po7B-2q4dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		3 / 3 LEU A 112
PRO A 113
LEU A  53
 None
 0.50A 2qd5B-2q4dA:
undetectable		 2qd5B-2q4dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		5 / 9 ALA A 167
GLY A 132
ILE A 133
VAL A 138
ILE A 170
 None
 1.01A 3ekvB-2q4dA:
undetectable		 3ekvB-2q4dA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		5 / 12 LEU A 141
ALA A 111
GLY A 145
ILE A 110
ARG A 168
 None
 1.25A 3gyqA-2q4dA:
undetectable
3gyqB-2q4dA:
undetectable		 3gyqA-2q4dA:
27.18
3gyqB-2q4dA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		3 / 3 LEU A 112
PRO A 113
LEU A  53
 None
 0.35A 3hcrA-2q4dA:
2.9		 3hcrA-2q4dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		5 / 10 ALA A 167
GLY A 132
ILE A 133
VAL A 138
ILE A 170
 None
 1.05A 4dqcA-2q4dA:
undetectable		 4dqcA-2q4dA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950
(Arabidopsis
thaliana) 		5 / 10 ALA A 167
GLY A 132
ILE A 133
VAL A 138
ILE A 170
 None
 1.01A 4q1wB-2q4dA:
undetectable		 4q1wB-2q4dA:
20.12