SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q4f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 2q4f HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Oryza
sativa) 		4 / 8 MET A 134
LEU A  14
VAL A  89
GLY A  90
 None
 1.03A 2qd5A-2q4fA:
undetectable		 2qd5A-2q4fA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 2q4f HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Oryza
sativa) 		5 / 9 ASP A  76
VAL A  75
GLY A 112
ALA A  62
ILE A  61
 None
 1.01A 3ektB-2q4fA:
undetectable		 3ektB-2q4fA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2q4f HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Oryza
sativa) 		4 / 6 ALA A  54
ILE A  58
LEU A  82
ALA A  91
 None
 0.87A 3r9sA-2q4fA:
undetectable		 3r9sA-2q4fA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 2q4f HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Oryza
sativa) 		4 / 6 LEU A  14
LEU A 135
PHE A 131
VAL A  23
 None
 1.12A 4udaA-2q4fA:
undetectable		 4udaA-2q4fA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 2q4f HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Oryza
sativa) 		3 / 3 VAL A  79
GLN A 103
CYH A 105
 None
 0.88A 5icxC-2q4fA:
undetectable
5icxF-2q4fA:
undetectable		 5icxC-2q4fA:
20.77
5icxF-2q4fA:
9.68