SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q4n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_C_TFPC208_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2q4n	UNCHARACTERIZED PROTEIN AT1G79260 (Arabidopsis thaliana)	4 / 5	PHE A 135 LEU A 163 PHE A 82 SER A 53	None	1.08A	1wrlC-2q4nA: undetectable	1wrlC-2q4nA: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_PCFA1179_1 (WNT INHIBITORY FACTOR 1)	2q4n	UNCHARACTERIZED PROTEIN AT1G79260 (Arabidopsis thaliana)	4 / 5	ILE A 60 PHE A 135 PRO A 84 VAL A 128	None	0.84A	2ygnA-2q4nA: undetectable	2ygnA-2q4nA: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1479_0 (TRANSLATION ELONGATION FACTOR SELB)	2q4n	UNCHARACTERIZED PROTEIN AT1G79260 (Arabidopsis thaliana)	4 / 5	THR A 63 ILE A 50 GLU A 48 PHE A 135	None	1.42A	4acbC-2q4nA: undetectable	4acbC-2q4nA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_F_377F401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2q4n	UNCHARACTERIZED PROTEIN AT1G79260 (Arabidopsis thaliana)	4 / 7	GLU A 48 GLU A 78 LEU A 117 TYR A 144	None	1.00A	4twdF-2q4nA: undetectable 4twdJ-2q4nA: undetectable	4twdF-2q4nA: 21.80 4twdJ-2q4nA: 21.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_C_TFPC208_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2q4n","UNCHARACTERIZED PROTEIN AT1G79260","Arabidopsis thaliana",4,"PHE A 135;LEU A 163;PHE A  82;SER A  53","None","1.08A","1wrlC-2q4nA:undetectable","1wrlC-2q4nA:19.77"],["2YGN_A_PCFA1179_1","WNT INHIBITORY FACTOR 1","2q4n","UNCHARACTERIZED PROTEIN AT1G79260","Arabidopsis thaliana",4,"ILE A  60;PHE A 135;PRO A  84;VAL A 128","None","0.84A","2ygnA-2q4nA:undetectable","2ygnA-2q4nA:22.02"],["4ACB_C_DXCC1479_0","TRANSLATION ELONGATION FACTOR SELB","2q4n","UNCHARACTERIZED PROTEIN AT1G79260","Arabidopsis thaliana",4,"THR A  63;ILE A  50;GLU A  48;PHE A 135","None","1.42A","4acbC-2q4nA:undetectable","4acbC-2q4nA:18.34"],["4TWD_F_377F401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","2q4n","UNCHARACTERIZED PROTEIN AT1G79260","Arabidopsis thaliana",4,"GLU A  48;GLU A  78;LEU A 117;TYR A 144","None","1.00A","4twdF-2q4nA:undetectable;4twdJ-2q4nA:undetectable","4twdF-2q4nA:21.80;4twdJ-2q4nA:21.80"]]