SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_D_DXCD92_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2q4v	DIAMINE ACETYLTRANSFERASE 2 (Homo sapiens)	4 / 5	VAL A 96 GLU A 8 LYS A 112 LYS A 108	ACO A 306 (-3.9A) None None None	1.38A	3rv5C-2q4vA: 0.0 3rv5D-2q4vA: 0.0	3rv5C-2q4vA: 18.34 3rv5D-2q4vA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_B_CQAB303_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	2q4v	DIAMINE ACETYLTRANSFERASE 2 (Homo sapiens)	4 / 8	GLY A 106 GLY A 73 GLU A 23 LEU A 20	ACO A 306 (-3.2A) None None None	0.79A	4mwzB-2q4vA: undetectable	4mwzB-2q4vA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WW7_A_ACTA305_0 (EKC/KEOPS COMPLEX SUBUNIT BUD32)	2q4v	DIAMINE ACETYLTRANSFERASE 2 (Homo sapiens)	4 / 6	LEU A 127 LEU A 91 GLU A 92 ILE A 94	ACO A 306 (-3.3A) None None ACO A 306 (-3.6A)	0.80A	4ww7A-2q4vA: undetectable	4ww7A-2q4vA: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_H_CVIH301_1 (REGULATORY PROTEIN TETR)	2q4v	DIAMINE ACETYLTRANSFERASE 2 (Homo sapiens)	4 / 8	GLY A 75 ILE A 6 GLN A 103 ASP A 13	None	1.03A	5vlmH-2q4vA: undetectable	5vlmH-2q4vA: 18.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3RV5_D_DXCD92_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2q4v","DIAMINE ACETYLTRANSFERASE 2","Homo sapiens",4,"VAL A  96;GLU A   8;LYS A 112;LYS A 108","ACO A 306 (-3.9A);None;None;None","1.38A","3rv5C-2q4vA:0.0;3rv5D-2q4vA:0.0","3rv5C-2q4vA:18.34;3rv5D-2q4vA:18.34"],["4MWZ_B_CQAB303_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","2q4v","DIAMINE ACETYLTRANSFERASE 2","Homo sapiens",4,"GLY A 106;GLY A  73;GLU A  23;LEU A  20","ACO A 306 (-3.2A);None;None;None","0.79A","4mwzB-2q4vA:undetectable","4mwzB-2q4vA:20.59"],["4WW7_A_ACTA305_0","EKC\/KEOPS COMPLEX SUBUNIT BUD32","2q4v","DIAMINE ACETYLTRANSFERASE 2","Homo sapiens",4,"LEU A 127;LEU A  91;GLU A  92;ILE A  94","ACO A 306 (-3.3A);None;None;ACO A 306 (-3.6A)","0.80A","4ww7A-2q4vA:undetectable","4ww7A-2q4vA:21.29"],["5VLM_H_CVIH301_1","REGULATORY PROTEIN TETR","2q4v","DIAMINE ACETYLTRANSFERASE 2","Homo sapiens",4,"GLY A  75;ILE A   6;GLN A 103;ASP A  13","None","1.03A","5vlmH-2q4vA:undetectable","5vlmH-2q4vA:18.31"]]