SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q62'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 2q62 ARSH
(Sinorhizobium
meliloti) 		4 / 5 TRP A 123
ALA A  81
LEU A  76
ALA A  82
 None
 1.13A 2jstA-2q62A:
undetectable
2jstB-2q62A:
undetectable		 2jstA-2q62A:
15.35
2jstB-2q62A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 2q62 ARSH
(Sinorhizobium
meliloti) 		4 / 6 TRP A 104
LEU A  38
SER A  96
THR A 134
 None
 1.48A 3ropA-2q62A:
3.2		 3ropA-2q62A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 2q62 ARSH
(Sinorhizobium
meliloti) 		4 / 4 MET A 142
SER A 173
LEU A  53
VAL A 175
 None
 1.49A 3vlnA-2q62A:
0.8		 3vlnA-2q62A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2q62 ARSH
(Sinorhizobium
meliloti) 		4 / 4 LEU A  76
ALA A 119
ILE A 116
LYS A  88
 None
 1.33A 4eixA-2q62A:
1.6		 4eixA-2q62A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 2q62 ARSH
(Sinorhizobium
meliloti) 		4 / 6 ALA A  54
LEU A  52
SER A  48
VAL A  70
 None
None
SO4  A2001 (-2.7A)
None
 1.26A 5a6iA-2q62A:
undetectable		 5a6iA-2q62A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2q62 ARSH
(Sinorhizobium
meliloti) 		5 / 9 LEU A  76
ILE A 116
ILE A 124
VAL A  84
GLU A  91
 None
 1.34A 5igzA-2q62A:
undetectable		 5igzA-2q62A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2q62 ARSH
(Sinorhizobium
meliloti) 		5 / 12 ASP A 122
ILE A 121
ILE A 116
GLY A 115
LEU A  40
 None
 0.94A 5twjC-2q62A:
undetectable		 5twjC-2q62A:
22.13