SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q6k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		6 / 7 ASP A 183
PHE A 186
ASN A 188
TRP A 190
PHE A 228
SER A 242
 PEG  A 402 (-2.9A)
None
None
None
None
PEG  A 402 (-3.3A)
 0.79A 1rqpB-2q6kA:
31.4		 1rqpB-2q6kA:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		6 / 8 ASP A 183
PHE A 186
ASN A 188
TRP A 190
PHE A 228
SER A 242
 PEG  A 402 (-2.9A)
None
None
None
None
PEG  A 402 (-3.3A)
 0.80A 1rqpC-2q6kA:
31.5		 1rqpC-2q6kA:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		6 / 8 ASP A 183
PHE A 186
ASN A 188
TRP A 190
PHE A 228
SER A 242
 PEG  A 402 (-2.9A)
None
None
None
None
PEG  A 402 (-3.3A)
 0.80A 1rqpA-2q6kA:
31.6		 1rqpA-2q6kA:
38.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 6 LEU A   9
PHE A   8
ALA A   7
LEU A  54
 None
 0.99A 1ukbA-2q6kA:
undetectable		 1ukbA-2q6kA:
23.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 2q6k CHLORINASE
(Salinispora
tropica) 		7 / 7 ASP A  11
VAL A  12
ALA A  18
PHE A  45
PRO A  73
THR A  75
TRP A 129
 ADN  A 699 (-2.9A)
None
None
ADN  A 699 (-4.4A)
ADN  A 699 (-4.0A)
ADN  A 699 (-3.4A)
None
 0.21A 2q6oA-2q6kA:
40.1		 2q6oA-2q6kA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 2q6k CHLORINASE
(Salinispora
tropica) 		6 / 6 ASP A  11
VAL A  12
PHE A  45
PRO A  73
THR A  75
TRP A 129
 ADN  A 699 (-2.9A)
None
ADN  A 699 (-4.4A)
ADN  A 699 (-4.0A)
ADN  A 699 (-3.4A)
None
 0.22A 2q6oB-2q6kA:
40.2		 2q6oB-2q6kA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 6 VAL A  12
PHE A  45
THR A 128
TRP A 129
 None
ADN  A 699 (-4.4A)
None
None
 1.45A 2q6oB-2q6kA:
40.2		 2q6oB-2q6kA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		6 / 8 ASP A 183
PHE A 186
ASN A 188
TRP A 190
PHE A 228
SER A 242
 PEG  A 402 (-2.9A)
None
None
None
None
PEG  A 402 (-3.3A)
 0.82A 2v7uA-2q6kA:
31.5		 2v7uA-2q6kA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		6 / 7 ASP A 183
PHE A 186
ASN A 188
TRP A 190
PHE A 228
SER A 242
 PEG  A 402 (-2.9A)
None
None
None
None
PEG  A 402 (-3.3A)
 0.83A 2v7uB-2q6kA:
31.4		 2v7uB-2q6kA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V7U_B_SAMB1300_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		7 / 9 ASP A 183
PHE A 186
ASN A 188
TRP A 190
PHE A 228
SER A 242
ASN A 251
 PEG  A 402 (-2.9A)
None
None
None
None
PEG  A 402 (-3.3A)
None
 0.77A 2v7uC-2q6kA:
31.5		 2v7uC-2q6kA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZBU_A_ADNA501_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 4 PHE A 186
ASN A 188
PHE A 228
ASN A 251
 None
 0.23A 2zbuA-2q6kA:
31.6		 2zbuA-2q6kA:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZBU_C_ADNC503_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 4 PHE A 186
ASN A 188
PHE A 228
ASN A 251
 None
 0.16A 2zbuC-2q6kA:
31.6		 2zbuC-2q6kA:
32.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2q6k CHLORINASE
(Salinispora
tropica) 		3 / 3 PHE A 186
ASN A 188
PHE A 228
 None
 0.14A 2zbuD-2q6kA:
31.4		 2zbuD-2q6kA:
32.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 4 LYS A   1
LEU A  92
MET A  26
ARG A 154
 None
 1.38A 4bkjA-2q6kA:
0.0		 4bkjA-2q6kA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 5 LYS A   1
LEU A  92
MET A  26
ARG A 154
 None
 1.36A 4bkjB-2q6kA:
undetectable		 4bkjB-2q6kA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 2q6k CHLORINASE
(Salinispora
tropica) 		5 / 12 SER A 266
ILE A 193
PRO A 194
ILE A 175
ARG A 245
 None
 1.38A 4uroD-2q6kA:
undetectable		 4uroD-2q6kA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		5 / 12 GLU A 111
HIS A 113
VAL A 115
VAL A 151
LEU A 142
 None
 1.35A 4ygfE-2q6kA:
undetectable		 4ygfE-2q6kA:
21.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B6I_A_ADNA302_1
(FLUORINASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 7 ASP A  11
TYR A  72
PRO A  73
THR A  75
 ADN  A 699 (-2.9A)
None
ADN  A 699 (-4.0A)
ADN  A 699 (-3.4A)
 0.39A 5b6iA-2q6kA:
31.6		 5b6iA-2q6kA:
36.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 8 ASN A 254
LEU A 250
GLY A 249
VAL A 189
 None
 0.84A 5m8rC-2q6kA:
undetectable		 5m8rC-2q6kA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2q6k CHLORINASE
(Salinispora
tropica) 		5 / 10 ALA A 143
PHE A  61
ILE A  67
VAL A  36
ALA A  33
 None
 1.20A 5nukA-2q6kA:
undetectable		 5nukA-2q6kA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 2q6k CHLORINASE
(Salinispora
tropica) 		5 / 10 LEU A  92
VAL A  93
LEU A 104
GLU A 111
ILE A 160
 None
 0.96A 5v02B-2q6kA:
undetectable
5v02R-2q6kA:
undetectable		 5v02B-2q6kA:
14.69
5v02R-2q6kA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2q6k CHLORINASE
(Salinispora
tropica) 		5 / 12 GLU A 257
VAL A 179
VAL A 189
GLY A 187
ILE A 256
 None
 1.01A 5vopA-2q6kA:
undetectable		 5vopA-2q6kA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2q6k CHLORINASE
(Salinispora
tropica) 		4 / 8 LYS A 132
THR A 128
THR A  75
PRO A 124
 None
None
ADN  A 699 (-3.4A)
None
 1.13A 5x2sI-2q6kA:
undetectable
5x2sJ-2q6kA:
undetectable
5x2sK-2q6kA:
undetectable		 5x2sI-2q6kA:
20.49
5x2sJ-2q6kA:
18.73
5x2sK-2q6kA:
20.49