SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q7b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9Q_A_CHDA459_0 (ESTROGEN-RELATED RECEPTOR GAMMA)	2q7b	ACETYLTRANSFERASE, GNAT FAMILY (Streptococcus agalactiae)	4 / 6	ASP A 118 LEU A 117 VAL A 116 ILE A 115	FLC A 164 (-3.2A) None None None	0.80A	1s9qA-2q7bA: undetectable	1s9qA-2q7bA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_A_CHDA130_1 (FATTY ACID-BINDING PROTEIN)	2q7b	ACETYLTRANSFERASE, GNAT FAMILY (Streptococcus agalactiae)	3 / 3	TYR A 130 ARG A 152 GLN A 24	None FLC A 164 (-4.3A) FLC A 164 (-3.9A)	0.82A	1tw4A-2q7bA: undetectable	1tw4A-2q7bA: 25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_D_PARD500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	2q7b	ACETYLTRANSFERASE, GNAT FAMILY (Streptococcus agalactiae)	4 / 8	SER A 110 ASP A 74 ASP A 73 TYR A 147	None None None FLC A 164 (-4.7A)	1.26A	4qb9D-2q7bA: 10.6	4qb9D-2q7bA: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EDL_A_VIBA201_1 (PUTATIVE HMP/THIAMINE PERMEASE PROTEIN YKOE)	2q7b	ACETYLTRANSFERASE, GNAT FAMILY (Streptococcus agalactiae)	5 / 12	TYR A 47 VAL A 17 ILE A 20 GLN A 37 SER A 66	None None None FLC A 164 (-4.4A) None	1.43A	5edlA-2q7bA: 0.0	5edlA-2q7bA: 19.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9Q_A_CHDA459_0","ESTROGEN-RELATED RECEPTOR GAMMA","2q7b","ACETYLTRANSFERASE, GNAT FAMILY","Streptococcus agalactiae",4,"ASP A 118;LEU A 117;VAL A 116;ILE A 115","FLC A 164 (-3.2A);None;None;None","0.80A","1s9qA-2q7bA:undetectable","1s9qA-2q7bA:22.14"],["1TW4_A_CHDA130_1","FATTY ACID-BINDING PROTEIN","2q7b","ACETYLTRANSFERASE, GNAT FAMILY","Streptococcus agalactiae",3,"TYR A 130;ARG A 152;GLN A  24","None;FLC A 164 (-4.3A);FLC A 164 (-3.9A)","0.82A","1tw4A-2q7bA:undetectable","1tw4A-2q7bA:25.68"],["4QB9_D_PARD500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","2q7b","ACETYLTRANSFERASE, GNAT FAMILY","Streptococcus agalactiae",4,"SER A 110;ASP A  74;ASP A  73;TYR A 147","None;None;None;FLC A 164 (-4.7A)","1.26A","4qb9D-2q7bA:10.6","4qb9D-2q7bA:18.31"],["5EDL_A_VIBA201_1","PUTATIVE HMP\/THIAMINE PERMEASE PROTEIN YKOE","2q7b","ACETYLTRANSFERASE, GNAT FAMILY","Streptococcus agalactiae",5,"TYR A  47;VAL A  17;ILE A  20;GLN A  37;SER A  66","None;None;None;FLC A 164 (-4.4A);None","1.43A","5edlA-2q7bA:0.0","5edlA-2q7bA:19.61"]]