SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 7 VAL A 333
THR A 363
LEU A 362
VAL A 349
 None
 0.90A 1jgsA-2q7nA:
undetectable		 1jgsA-2q7nA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 7 ILE A 310
PRO A 307
ASN A 366
ASN A 318
 None
 0.91A 1oniG-2q7nA:
undetectable
1oniI-2q7nA:
undetectable		 1oniG-2q7nA:
15.30
1oniI-2q7nA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 8 LEU A  79
GLU A  81
THR A  12
LEU A   8
 None
 0.93A 1sn5C-2q7nA:
undetectable		 1sn5C-2q7nA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 7 GLY A 308
PRO A 288
ASN A 306
GLY A 364
 None
 0.81A 3tajA-2q7nA:
undetectable		 3tajA-2q7nA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 8 VAL A 213
VAL A 279
ILE A 234
ILE A 253
 None
 0.76A 3warA-2q7nA:
undetectable		 3warA-2q7nA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 6 GLU A 125
LYS A 127
TRP A 190
GLU A 135
 None
 1.36A 4a7tA-2q7nA:
3.7		 4a7tA-2q7nA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 6 GLU A 125
LYS A 127
TRP A 190
GLU A 135
 None
 1.32A 4a7tF-2q7nA:
2.8		 4a7tF-2q7nA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 9 VAL A 279
VAL A 278
ILE A 253
SER A 259
ALA A 281
 None
 1.18A 4fwdA-2q7nA:
undetectable		 4fwdA-2q7nA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 7 GLN A 247
THR A 227
THR A 270
THR A 202
 None
 1.08A 4mbsA-2q7nA:
undetectable		 4mbsA-2q7nA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 12 ALA A  98
ILE A 126
ILE A 196
VAL A 170
VAL A 128
 None
 0.84A 4nkxA-2q7nA:
undetectable		 4nkxA-2q7nA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 12 ALA A  98
ILE A 126
ILE A 196
VAL A 170
VAL A 128
 None
 0.86A 4nkxB-2q7nA:
undetectable		 4nkxB-2q7nA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 11 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.19A 4ygfA-2q7nA:
undetectable		 4ygfA-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 11 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.17A 4ygfC-2q7nA:
undetectable		 4ygfC-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 11 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.18A 4ygfD-2q7nA:
undetectable		 4ygfD-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 12 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.18A 4ygfG-2q7nA:
undetectable		 4ygfG-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 12 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.18A 4yhaA-2q7nA:
undetectable		 4yhaA-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 12 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.18A 4yhaE-2q7nA:
undetectable		 4yhaE-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 12 GLY A 216
SER A 217
MET A 219
GLY A 263
SER A 259
 None
 1.18A 5hikA-2q7nA:
undetectable		 5hikA-2q7nA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 7 ILE A 126
TRP A 157
TRP A 155
SER A 159
 None
 1.40A 5nr3A-2q7nA:
undetectable		 5nr3A-2q7nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		3 / 3 HIS A 175
GLU A 186
TRP A 187
 None
 1.16A 5odiD-2q7nA:
undetectable		 5odiD-2q7nA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		3 / 3 HIS A 175
GLU A 186
TRP A 187
 None
 1.09A 5odqD-2q7nA:
undetectable		 5odqD-2q7nA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		3 / 3 HIS A 175
GLU A 186
TRP A 187
 None
 1.11A 5odrD-2q7nA:
undetectable		 5odrD-2q7nA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 10 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.14A 5tt3A-2q7nA:
undetectable		 5tt3A-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 9 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.12A 5tt3B-2q7nA:
undetectable		 5tt3B-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 10 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.10A 5tt3C-2q7nA:
undetectable		 5tt3C-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 9 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.22A 5tt3E-2q7nA:
undetectable		 5tt3E-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		5 / 9 HIS A 168
VAL A 170
VAL A 128
ALA A  98
TRP A 157
 None
 1.21A 5tt3G-2q7nA:
undetectable		 5tt3G-2q7nA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR
(Mus
musculus) 		4 / 8 HIS A 168
VAL A 170
ALA A  98
TRP A 157
 None
 0.81A 5tt3H-2q7nA:
undetectable		 5tt3H-2q7nA:
19.54