SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 4 THR A  75
PRO A  77
THR A  34
PRO A  37
 None
 1.23A 1a7yA-2q7sA:
undetectable
1a7yC-2q7sA:
undetectable		 1a7yA-2q7sA:
6.33
1a7yC-2q7sA:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ARG A 252
ASP A  82
TRP A 117
ARG A 180
 None
 1.29A 1ceaB-2q7sA:
undetectable		 1ceaB-2q7sA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ARG A 252
ASP A  82
TRP A 117
ARG A 180
 None
 1.47A 1cebA-2q7sA:
undetectable		 1cebA-2q7sA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 5 GLU A 258
ARG A  78
LYS A 114
ASP A  82
 None
ZN  A 400 ( 4.3A)
None
None
 1.36A 1k4tA-2q7sA:
0.0		 1k4tA-2q7sA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 ARG A 261
ARG A  48
ARG A 252
 None
 1.08A 1l7fA-2q7sA:
undetectable		 1l7fA-2q7sA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 ARG A 261
ARG A  48
ARG A 252
 None
 1.10A 1l7hA-2q7sA:
undetectable		 1l7hA-2q7sA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 ILE A 116
ILE A  81
THR A 109
 None
 0.65A 1rg7A-2q7sA:
undetectable		 1rg7A-2q7sA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		5 / 12 HIS A 171
ASN A 169
ILE A  81
ALA A  73
LEU A 151
 ZN  A 400 (-3.0A)
None
None
None
None
 1.17A 1udtA-2q7sA:
undetectable		 1udtA-2q7sA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		5 / 11 GLU A  53
ILE A  81
ALA A  74
PRO A  37
PHE A  40
 None
 1.28A 2admA-2q7sA:
undetectable		 2admA-2q7sA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.92A 2eijN-2q7sA:
undetectable
2eijW-2q7sA:
undetectable		 2eijN-2q7sA:
19.19
2eijW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.95A 2eikN-2q7sA:
undetectable
2eikW-2q7sA:
undetectable		 2eikN-2q7sA:
19.19
2eikW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.92A 2eilN-2q7sA:
undetectable
2eilW-2q7sA:
undetectable		 2eilN-2q7sA:
19.19
2eilW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.91A 2einA-2q7sA:
undetectable
2einJ-2q7sA:
undetectable		 2einA-2q7sA:
19.19
2einJ-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 LEU A  23
PRO A  24
ARG A 280
 None
 0.51A 2qd5A-2q7sA:
undetectable		 2qd5A-2q7sA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		5 / 11 SER A  32
SER A  29
ALA A  74
GLY A  33
PHE A  76
 None
 1.49A 2xf3A-2q7sA:
undetectable		 2xf3A-2q7sA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		5 / 11 SER A  32
SER A  29
ALA A  74
GLY A  33
PHE A  76
 None
 1.49A 2xf3B-2q7sA:
undetectable		 2xf3B-2q7sA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		5 / 10 SER A  32
SER A  29
ALA A  74
GLY A  33
PHE A  76
 None
 1.49A 2xh9B-2q7sA:
undetectable		 2xh9B-2q7sA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.98A 2zxwN-2q7sA:
undetectable
2zxwW-2q7sA:
undetectable		 2zxwN-2q7sA:
19.19
2zxwW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.91A 3abkA-2q7sA:
undetectable
3abkJ-2q7sA:
undetectable		 3abkA-2q7sA:
19.19
3abkJ-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.93A 3ag2N-2q7sA:
undetectable
3ag2W-2q7sA:
undetectable		 3ag2N-2q7sA:
19.19
3ag2W-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.90A 3ag4N-2q7sA:
undetectable
3ag4W-2q7sA:
undetectable		 3ag4N-2q7sA:
19.19
3ag4W-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.94A 3asnN-2q7sA:
0.0
3asnW-2q7sA:
undetectable		 3asnN-2q7sA:
19.19
3asnW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.89A 3asoN-2q7sA:
undetectable
3asoW-2q7sA:
undetectable		 3asoN-2q7sA:
19.19
3asoW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 LEU A 270
GLN A 247
LEU A 206
LEU A 214
 None
 0.95A 3g8iA-2q7sA:
undetectable		 3g8iA-2q7sA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		5 / 12 VAL A  57
ALA A  59
LEU A  60
ILE A 281
LEU A 168
 None
 1.04A 3mb5A-2q7sA:
undetectable		 3mb5A-2q7sA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 HIS A  56
ARG A 263
GLU A 262
 None
 1.15A 3qf1A-2q7sA:
undetectable		 3qf1A-2q7sA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 LEU A  23
PRO A  24
ARG A 280
 None
 0.57A 4klrB-2q7sA:
undetectable		 4klrB-2q7sA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 ARG A  78
ASP A  54
ARG A  85
 ZN  A 400 ( 4.3A)
ZN  A 400 (-2.4A)
None
 0.78A 4mx0A-2q7sA:
undetectable		 4mx0A-2q7sA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ARG A 197
THR A 200
GLY A 199
THR A 201
 None
 0.99A 4qwpB-2q7sA:
undetectable		 4qwpB-2q7sA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A  16
PHE A  13
THR A  75
ASN A  84
LEU A 151
 None
 1.14A 4z7fC-2q7sA:
undetectable		 4z7fC-2q7sA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 6 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.93A 5b1aN-2q7sA:
undetectable
5b1aW-2q7sA:
undetectable		 5b1aN-2q7sA:
19.19
5b1aW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.81A 5b3sN-2q7sA:
undetectable
5b3sW-2q7sA:
undetectable		 5b3sN-2q7sA:
19.19
5b3sW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 6 LEU A 206
CYH A  27
HIS A 167
LEU A 168
 None
 1.11A 5hpuC-2q7sA:
undetectable
5hpuD-2q7sA:
undetectable		 5hpuC-2q7sA:
6.67
5hpuD-2q7sA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.87A 5iy5N-2q7sA:
undetectable
5iy5W-2q7sA:
undetectable		 5iy5N-2q7sA:
19.19
5iy5W-2q7sA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 GLY A  52
ARG A  85
VAL A  79
ASP A  82
 None
 0.92A 5vlmA-2q7sA:
undetectable		 5vlmA-2q7sA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 5 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.86A 5z84N-2q7sA:
undetectable
5z84W-2q7sA:
undetectable		 5z84N-2q7sA:
19.19
5z84W-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.91A 5zcoA-2q7sA:
undetectable
5zcoJ-2q7sA:
undetectable		 5zcoA-2q7sA:
19.19
5zcoJ-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.85A 5zcpN-2q7sA:
undetectable
5zcpW-2q7sA:
undetectable		 5zcpN-2q7sA:
19.19
5zcpW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 8 ILE A 250
PHE A 192
ARG A 272
THR A 275
 None
 0.90A 5zcqN-2q7sA:
undetectable
5zcqW-2q7sA:
undetectable		 5zcqN-2q7sA:
19.19
5zcqW-2q7sA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		4 / 7 ASN A 176
ARG A 180
GLU A 258
ARG A 252
 None
 1.22A 6b8kA-2q7sA:
undetectable		 6b8kA-2q7sA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE
(Cupriavidus
pinatubonensis) 		3 / 3 ASP A 225
ASP A 191
ASN A 264
 None
 0.79A 6gngB-2q7sA:
undetectable		 6gngB-2q7sA:
20.80