SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		5 / 12 GLY A 170
THR A 136
GLY A  58
LEU A  60
LEU A  55
 None
 1.00A 2hw2A-2q7tA:
undetectable		 2hw2A-2q7tA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		3 / 3 LEU A  82
MET A   2
MET A  29
 None
 0.92A 2vavF-2q7tA:
undetectable		 2vavF-2q7tA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		4 / 8 GLN A 155
HIS A 157
HIS A 159
HIS A 146
 None
MG  A5001 (-3.9A)
MG  A5001 (-3.7A)
MG  A5001 (-3.8A)
 0.77A 3w6hA-2q7tA:
undetectable		 3w6hA-2q7tA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		4 / 8 PRO A  87
SER A  89
VAL A  90
GLY A 222
 None
 0.88A 4mk4A-2q7tA:
undetectable		 4mk4A-2q7tA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		5 / 12 GLY A  35
GLY A  37
ALA A 163
LEU A  55
GLY A 137
 None
 0.90A 5kb5A-2q7tA:
undetectable		 5kb5A-2q7tA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		4 / 5 VAL A 110
THR A 158
ASN A 145
LEU A 143
 None
 1.27A 5m0iB-2q7tA:
undetectable		 5m0iB-2q7tA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		5 / 11 GLY A 184
GLU A 187
SER A 176
LEU A 175
ASN A 164
 None
 1.09A 5x6yA-2q7tA:
undetectable		 5x6yA-2q7tA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 2q7t PROTEIN TRAI
(Escherichia
coli) 		5 / 10 GLY A 184
GLU A 187
SER A 176
LEU A 175
ASN A 164
 None
 1.12A 5x6yB-2q7tA:
undetectable		 5x6yB-2q7tA:
17.91