SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q83'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 247
MET A 141
LEU A 144
ILE A 274
LEU A 131
 None
 1.14A 1errA-2q83A:
undetectable		 1errA-2q83A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ALA A  81
PHE A  83
ALA A  87
LEU A  91
LEU A 235
 None
 1.17A 2bxqA-2q83A:
undetectable		 2bxqA-2q83A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gB-2q83A:
undetectable		 3j6gB-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gD-2q83A:
undetectable		 3j6gD-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gF-2q83A:
undetectable		 3j6gF-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gH-2q83A:
undetectable		 3j6gH-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gJ-2q83A:
undetectable		 3j6gJ-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gL-2q83A:
undetectable		 3j6gL-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gN-2q83A:
undetectable		 3j6gN-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gP-2q83A:
undetectable		 3j6gP-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 264
LEU A 258
SER A 151
THR A 245
LEU A 144
 None
 1.41A 3j6gR-2q83A:
undetectable		 3j6gR-2q83A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A  82
SER A  84
PHE A  86
LEU A 117
ASP A 257
 None
 1.22A 3ko0A-2q83A:
undetectable
3ko0B-2q83A:
undetectable
3ko0C-2q83A:
undetectable
3ko0D-2q83A:
undetectable		 3ko0A-2q83A:
15.38
3ko0B-2q83A:
15.38
3ko0C-2q83A:
15.38
3ko0D-2q83A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 12 ASP A 257
LEU A  82
SER A  84
PHE A  86
LEU A 117
 None
 1.21A 3ko0G-2q83A:
undetectable
3ko0H-2q83A:
undetectable
3ko0I-2q83A:
undetectable
3ko0J-2q83A:
undetectable		 3ko0G-2q83A:
15.38
3ko0H-2q83A:
15.38
3ko0I-2q83A:
15.38
3ko0J-2q83A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 11 ASP A 257
LEU A 117
LEU A  82
SER A  84
PHE A  86
 None
 1.18A 3ko0A-2q83A:
undetectable
3ko0B-2q83A:
undetectable
3ko0I-2q83A:
undetectable
3ko0J-2q83A:
undetectable		 3ko0A-2q83A:
15.38
3ko0B-2q83A:
15.38
3ko0I-2q83A:
15.38
3ko0J-2q83A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A  82
SER A  84
PHE A  86
LEU A 117
ASP A 257
 None
 1.19A 3ko0K-2q83A:
undetectable
3ko0L-2q83A:
undetectable
3ko0S-2q83A:
undetectable
3ko0T-2q83A:
undetectable		 3ko0K-2q83A:
15.38
3ko0L-2q83A:
15.38
3ko0S-2q83A:
15.38
3ko0T-2q83A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 117
LEU A  82
SER A  84
PHE A  86
ASP A 257
 None
 1.18A 3ko0K-2q83A:
undetectable
3ko0L-2q83A:
undetectable
3ko0M-2q83A:
undetectable
3ko0N-2q83A:
undetectable		 3ko0K-2q83A:
15.38
3ko0L-2q83A:
15.38
3ko0M-2q83A:
15.38
3ko0N-2q83A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 12 ASP A 257
LEU A 117
LEU A  82
SER A  84
PHE A  86
 None
 1.12A 3ko0M-2q83A:
undetectable
3ko0N-2q83A:
undetectable
3ko0O-2q83A:
undetectable
3ko0P-2q83A:
undetectable		 3ko0M-2q83A:
15.38
3ko0N-2q83A:
15.38
3ko0O-2q83A:
15.38
3ko0P-2q83A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 11 LYS A  72
PRO A  99
ILE A 124
LEU A 246
ILE A 256
 None
ADN  A   1 ( 4.9A)
ADN  A   1 (-4.6A)
None
ADN  A   1 ( 4.6A)
 0.84A 4dt8A-2q83A:
14.7		 4dt8A-2q83A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 LYS A  72
PRO A  99
ILE A 124
LEU A 246
ILE A 256
 None
ADN  A   1 ( 4.9A)
ADN  A   1 (-4.6A)
None
ADN  A   1 ( 4.6A)
 0.87A 4dt8B-2q83A:
14.4		 4dt8B-2q83A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 10 LYS A  72
PRO A  99
ILE A 124
LEU A 246
ILE A 256
 None
ADN  A   1 ( 4.9A)
ADN  A   1 (-4.6A)
None
ADN  A   1 ( 4.6A)
 0.79A 4dtaA-2q83A:
15.2		 4dtaA-2q83A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 242
THR A 245
PHE A 139
 None
 0.90A 5cxvA-2q83A:
undetectable		 5cxvA-2q83A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		3 / 3 GLU A 319
TYR A 321
ARG A 176
 None
None
UNL  A   5 (-3.2A)
 0.85A 5uunA-2q83A:
undetectable		 5uunA-2q83A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		4 / 5 VAL A  69
PRO A  99
GLY A 100
TYR A 121
 None
ADN  A   1 ( 4.9A)
None
None
 1.12A 5x80A-2q83A:
undetectable
5x80B-2q83A:
undetectable		 5x80A-2q83A:
20.90
5x80B-2q83A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		4 / 5 PRO A  99
GLY A 100
TYR A 121
VAL A  69
 ADN  A   1 ( 4.9A)
None
None
None
 1.06A 5x80C-2q83A:
undetectable
5x80D-2q83A:
undetectable		 5x80C-2q83A:
20.90
5x80D-2q83A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 2q83 YTAA PROTEIN
(Bacillus
subtilis) 		5 / 12 TYR A 318
PRO A 317
LEU A 356
ASP A 313
MET A 310
 UNL  A   5 (-4.2A)
None
None
None
None
 1.36A 5yn6A-2q83A:
undetectable		 5yn6A-2q83A:
21.43