SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 LEU A  96
ALA A 204
ALA A  41
LEU A 224
PHE A 230
 None
 1.08A 1nr6A-2q88A:
undetectable		 1nr6A-2q88A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 LEU A  96
ALA A 204
LEU A 224
LEU A 221
PHE A 230
 None
 1.11A 1nr6A-2q88A:
undetectable		 1nr6A-2q88A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN
(Sinorhizobium
meliloti) 		5 / 10 PRO A  22
THR A  25
PRO A  38
GLY A  35
GLY A  28
 None
 1.36A 2vl2A-2q88A:
undetectable
2vl2C-2q88A:
undetectable		 2vl2A-2q88A:
25.00
2vl2C-2q88A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 ILE A 233
ILE A  18
LEU A 224
PHE A 230
 None
 1.15A 3adsA-2q88A:
undetectable		 3adsA-2q88A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN
(Sinorhizobium
meliloti) 		4 / 7 ASP A 218
PHE A 217
GLY A 203
PHE A 206
 None
 1.07A 3vnsA-2q88A:
3.2		 3vnsA-2q88A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 LEU A 171
VAL A 180
LEU A 179
ILE A 166
LEU A 104
 None
 1.10A 5og9B-2q88A:
undetectable		 5og9B-2q88A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 2q88 PUTATIVE ABC
TRANSPORTER AMINO
ACID-BINDING PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ALA A  88
PHE A 230
ALA A 241
ALA A 243
LEU A 252
 None
 1.36A 6aycA-2q88A:
undetectable		 6aycA-2q88A:
16.67