SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		6 / 10 LEU A 160
ILE A 168
LEU A 165
ASP A 185
LEU A 182
ILE A 167
 GOL  A 206 (-4.7A)
None
None
GOL  A 206 (-3.7A)
GOL  A 206 (-4.9A)
GOL  A 206 (-4.9A)
 1.24A 1yi4A-2q9rA:
undetectable		 1yi4A-2q9rA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		6 / 12 LEU A  53
ALA A 100
GLY A 106
ILE A 108
ALA A  52
ILE A 101
 None
 1.45A 2nmzB-2q9rA:
undetectable		 2nmzB-2q9rA:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		5 / 5 LEU A  36
GLY A  90
PRO A  93
ILE A 194
ILE A 196
 BEZ  A 203 ( 4.1A)
BEZ  A 203 (-3.5A)
BEZ  A 203 ( 4.6A)
None
BEZ  A 203 ( 4.4A)
 0.00A 2q9rA-2q9rA:
37.9		 2q9rA-2q9rA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		4 / 8 LEU A 164
SER A 163
ARG A  10
ILE A 168
 GOL  A 206 ( 4.9A)
GOL  A 206 (-2.9A)
None
None
 0.87A 3ln1A-2q9rA:
0.2		 3ln1A-2q9rA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		4 / 7 LEU A 164
SER A 163
ARG A  10
ILE A 168
 GOL  A 206 ( 4.9A)
GOL  A 206 (-2.9A)
None
None
 0.86A 3ln1B-2q9rA:
0.3		 3ln1B-2q9rA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		5 / 9 ALA A 100
ALA A 107
GLY A 106
ILE A 108
ILE A 116
 None
 1.10A 4eatB-2q9rA:
undetectable		 4eatB-2q9rA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		5 / 12 LEU A  53
ALA A 107
LEU A  60
ARG A 183
GLY A 181
 None
 1.23A 4l9qA-2q9rA:
2.1		 4l9qA-2q9rA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 2q9r PROTEIN OF UNKNOWN
FUNCTION
(Shewanella
baltica) 		4 / 7 THR A 126
ASP A  96
TYR A  89
GLY A  90
 None
None
None
BEZ  A 203 (-3.5A)
 1.06A 5hwaA-2q9rA:
2.0		 5hwaA-2q9rA:
21.24