SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_A_TDZA201_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	7 / 12	PHE A 16 VAL A 23 SER A 53 THR A 60 ALA A 75 ARG A 126 TYR A 128	None None EIC A 601 (-3.1A) None EIC A 601 ( 4.1A) EIC A 601 (-4.5A) EIC A 601 (-4.7A)	1.39A	2qm9A-2q9sA: 26.6	2qm9A-2q9sA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_A_TDZA201_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	12 / 12	PHE A 16 VAL A 25 ALA A 33 SER A 53 SER A 55 THR A 60 ALA A 75 ASP A 76 ARG A 78 CYH A 117 ARG A 126 TYR A 128	None None EIC A 601 (-3.5A) EIC A 601 (-3.1A) None None EIC A 601 ( 4.1A) EIC A 601 (-3.6A) EIC A 601 ( 4.9A) EIC A 601 (-3.3A) EIC A 601 (-4.5A) EIC A 601 (-4.7A)	0.37A	2qm9A-2q9sA: 26.6	2qm9A-2q9sA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_A_TDZA201_2 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 4	TYR A 19 MET A 20 PRO A 38 ILE A 104	None EIC A 601 ( 4.1A) EIC A 601 (-4.6A) EIC A 601 ( 4.5A)	0.24A	2qm9A-2q9sA: 26.6	2qm9A-2q9sA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_B_TDZB202_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	12 / 12	PHE A 16 TYR A 19 VAL A 25 SER A 53 SER A 55 THR A 60 ALA A 75 ARG A 78 ILE A 104 CYH A 117 ARG A 126 TYR A 128	None None None EIC A 601 (-3.1A) None None EIC A 601 ( 4.1A) EIC A 601 ( 4.9A) EIC A 601 ( 4.5A) EIC A 601 (-3.3A) EIC A 601 (-4.5A) EIC A 601 (-4.7A)	0.34A	2qm9B-2q9sA: 27.3	2qm9B-2q9sA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_B_TDZB202_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	7 / 12	PHE A 16 VAL A 23 SER A 53 THR A 60 ALA A 75 ARG A 126 TYR A 128	None None EIC A 601 (-3.1A) None EIC A 601 ( 4.1A) EIC A 601 (-4.5A) EIC A 601 (-4.7A)	1.33A	2qm9B-2q9sA: 27.3	2qm9B-2q9sA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_B_TDZB202_2 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 4	MET A 20 PRO A 38 ASP A 76 ARG A 106	EIC A 601 ( 4.1A) EIC A 601 (-4.6A) EIC A 601 (-3.6A) None	0.13A	2qm9B-2q9sA: 27.3	2qm9B-2q9sA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 6	ARG A 126 VAL A 115 ILE A 104 TYR A 128	EIC A 601 (-4.5A) EIC A 601 (-4.3A) EIC A 601 ( 4.5A) EIC A 601 (-4.7A)	1.13A	2yfbB-2q9sA: undetectable	2yfbB-2q9sA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9L_A_AZZA1009_1 (SERUM ALBUMIN)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 8	GLU A 72 SER A 82 GLN A 93 CYH A 117	None None None EIC A 601 (-3.3A)	1.18A	3b9lA-2q9sA: undetectable	3b9lA-2q9sA: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 7	PHE A 4 LEU A 91 LEU A 66 LEU A 86	None	0.70A	3bgdB-2q9sA: undetectable	3bgdB-2q9sA: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 7	GLN A 93 LEU A 48 ILE A 84 PHE A 64	None	1.04A	3ln1C-2q9sA: undetectable	3ln1C-2q9sA: 12.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3P6G_A_IZPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	12 / 12	PHE A 16 MET A 20 VAL A 25 PRO A 38 ASP A 76 ARG A 78 ILE A 104 ARG A 106 VAL A 115 CYH A 117 ARG A 126 TYR A 128	None EIC A 601 ( 4.1A) None EIC A 601 (-4.6A) EIC A 601 (-3.6A) EIC A 601 ( 4.9A) EIC A 601 ( 4.5A) None EIC A 601 (-4.3A) EIC A 601 (-3.3A) EIC A 601 (-4.5A) EIC A 601 (-4.7A)	0.55A	3p6gA-2q9sA: 25.7	3p6gA-2q9sA: 81.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3P6G_A_IZPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	5 / 12	PHE A 16 VAL A 23 PRO A 38 ARG A 126 TYR A 128	None None EIC A 601 (-4.6A) EIC A 601 (-4.5A) EIC A 601 (-4.7A)	1.29A	3p6gA-2q9sA: 25.7	3p6gA-2q9sA: 81.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3P6H_A_IBPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	7 / 7	PHE A 16 MET A 20 ASP A 76 ILE A 104 VAL A 115 ARG A 126 TYR A 128	None EIC A 601 ( 4.1A) EIC A 601 (-3.6A) EIC A 601 ( 4.5A) EIC A 601 (-4.3A) EIC A 601 (-4.5A) EIC A 601 (-4.7A)	0.54A	3p6hA-2q9sA: 25.7	3p6hA-2q9sA: 81.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4QZT_A_ACTA202_0 (RETINOL-BINDING PROTEIN 2)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 6	TYR A 19 GLU A 72 THR A 74 GLN A 95	None	0.81A	4qztA-2q9sA: 20.5	4qztA-2q9sA: 34.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4QZU_C_ACTC202_0 (RETINOL-BINDING PROTEIN 2)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	4 / 6	TYR A 19 GLU A 72 THR A 74 GLN A 95	None	0.81A	4qzuC-2q9sA: 20.6	4qzuC-2q9sA: 34.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H8T_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	5 / 12	PHE A 16 TYR A 19 ALA A 33 ILE A 51 SER A 55	None None EIC A 601 (-3.5A) None None	0.74A	5h8tA-2q9sA: 20.1	5h8tA-2q9sA: 31.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HBS_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	6 / 12	PHE A 16 TYR A 19 VAL A 25 ALA A 33 ILE A 51 SER A 55	None None None EIC A 601 (-3.5A) None None	0.83A	5hbsA-2q9sA: 20.0	5hbsA-2q9sA: 31.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HBS_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	2q9s	FATTY ACID-BINDING PROTEIN (Mus musculus)	6 / 12	PHE A 16 VAL A 25 ALA A 33 PRO A 38 ILE A 51 SER A 55	None None EIC A 601 (-3.5A) EIC A 601 (-4.6A) None None	0.88A	5hbsA-2q9sA: 20.0	5hbsA-2q9sA: 31.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QM9_A_TDZA201_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",7,"PHE A  16;VAL A  23;SER A  53;THR A  60;ALA A  75;ARG A 126;TYR A 128","None;None;EIC A 601 (-3.1A);None;EIC A 601 ( 4.1A);EIC A 601 (-4.5A);EIC A 601 (-4.7A)","1.39A","2qm9A-2q9sA:26.6","2qm9A-2q9sA:100.00"],["2QM9_A_TDZA201_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",12,"PHE A  16;VAL A  25;ALA A  33;SER A  53;SER A  55;THR A  60;ALA A  75;ASP A  76;ARG A  78;CYH A 117;ARG A 126;TYR A 128","None;None;EIC A 601 (-3.5A);EIC A 601 (-3.1A);None;None;EIC A 601 ( 4.1A);EIC A 601 (-3.6A);EIC A 601 ( 4.9A);EIC A 601 (-3.3A);EIC A 601 (-4.5A);EIC A 601 (-4.7A)","0.37A","2qm9A-2q9sA:26.6","2qm9A-2q9sA:100.00"],["2QM9_A_TDZA201_2","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"TYR A  19;MET A  20;PRO A  38;ILE A 104","None;EIC A 601 ( 4.1A);EIC A 601 (-4.6A);EIC A 601 ( 4.5A)","0.24A","2qm9A-2q9sA:26.6","2qm9A-2q9sA:100.00"],["2QM9_B_TDZB202_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",12,"PHE A  16;TYR A  19;VAL A  25;SER A  53;SER A  55;THR A  60;ALA A  75;ARG A  78;ILE A 104;CYH A 117;ARG A 126;TYR A 128","None;None;None;EIC A 601 (-3.1A);None;None;EIC A 601 ( 4.1A);EIC A 601 ( 4.9A);EIC A 601 ( 4.5A);EIC A 601 (-3.3A);EIC A 601 (-4.5A);EIC A 601 (-4.7A)","0.34A","2qm9B-2q9sA:27.3","2qm9B-2q9sA:100.00"],["2QM9_B_TDZB202_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",7,"PHE A  16;VAL A  23;SER A  53;THR A  60;ALA A  75;ARG A 126;TYR A 128","None;None;EIC A 601 (-3.1A);None;EIC A 601 ( 4.1A);EIC A 601 (-4.5A);EIC A 601 (-4.7A)","1.33A","2qm9B-2q9sA:27.3","2qm9B-2q9sA:100.00"],["2QM9_B_TDZB202_2","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"MET A  20;PRO A  38;ASP A  76;ARG A 106","EIC A 601 ( 4.1A);EIC A 601 (-4.6A);EIC A 601 (-3.6A);None","0.13A","2qm9B-2q9sA:27.3","2qm9B-2q9sA:100.00"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"ARG A 126;VAL A 115;ILE A 104;TYR A 128","EIC A 601 (-4.5A);EIC A 601 (-4.3A);EIC A 601 ( 4.5A);EIC A 601 (-4.7A)","1.13A","2yfbB-2q9sA:undetectable","2yfbB-2q9sA:19.25"],["3B9L_A_AZZA1009_1","SERUM ALBUMIN","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"GLU A  72;SER A  82;GLN A  93;CYH A 117","None;None;None;EIC A 601 (-3.3A)","1.18A","3b9lA-2q9sA:undetectable","3b9lA-2q9sA:14.31"],["3BGD_B_PM6B302_1","THIOPURINE S-METHYLTRANSFERASE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"PHE A   4;LEU A  91;LEU A  66;LEU A  86","None","0.70A","3bgdB-2q9sA:undetectable","3bgdB-2q9sA:21.22"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"GLN A  93;LEU A  48;ILE A  84;PHE A  64","None","1.04A","3ln1C-2q9sA:undetectable","3ln1C-2q9sA:12.59"],["3P6G_A_IZPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",12,"PHE A  16;MET A  20;VAL A  25;PRO A  38;ASP A  76;ARG A  78;ILE A 104;ARG A 106;VAL A 115;CYH A 117;ARG A 126;TYR A 128","None;EIC A 601 ( 4.1A);None;EIC A 601 (-4.6A);EIC A 601 (-3.6A);EIC A 601 ( 4.9A);EIC A 601 ( 4.5A);None;EIC A 601 (-4.3A);EIC A 601 (-3.3A);EIC A 601 (-4.5A);EIC A 601 (-4.7A)","0.55A","3p6gA-2q9sA:25.7","3p6gA-2q9sA:81.29"],["3P6G_A_IZPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",5,"PHE A  16;VAL A  23;PRO A  38;ARG A 126;TYR A 128","None;None;EIC A 601 (-4.6A);EIC A 601 (-4.5A);EIC A 601 (-4.7A)","1.29A","3p6gA-2q9sA:25.7","3p6gA-2q9sA:81.29"],["3P6H_A_IBPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",7,"PHE A  16;MET A  20;ASP A  76;ILE A 104;VAL A 115;ARG A 126;TYR A 128","None;EIC A 601 ( 4.1A);EIC A 601 (-3.6A);EIC A 601 ( 4.5A);EIC A 601 (-4.3A);EIC A 601 (-4.5A);EIC A 601 (-4.7A)","0.54A","3p6hA-2q9sA:25.7","3p6hA-2q9sA:81.29"],["4QZT_A_ACTA202_0","RETINOL-BINDING PROTEIN 2","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"TYR A  19;GLU A  72;THR A  74;GLN A  95","None","0.81A","4qztA-2q9sA:20.5","4qztA-2q9sA:34.00"],["4QZU_C_ACTC202_0","RETINOL-BINDING PROTEIN 2","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",4,"TYR A  19;GLU A  72;THR A  74;GLN A  95","None","0.81A","4qzuC-2q9sA:20.6","4qzuC-2q9sA:34.00"],["5H8T_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",5,"PHE A  16;TYR A  19;ALA A  33;ILE A  51;SER A  55","None;None;EIC A 601 (-3.5A);None;None","0.74A","5h8tA-2q9sA:20.1","5h8tA-2q9sA:31.21"],["5HBS_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",6,"PHE A  16;TYR A  19;VAL A  25;ALA A  33;ILE A  51;SER A  55","None;None;None;EIC A 601 (-3.5A);None;None","0.83A","5hbsA-2q9sA:20.0","5hbsA-2q9sA:31.21"],["5HBS_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","2q9s","FATTY ACID-BINDING PROTEIN","Mus musculus",6,"PHE A  16;VAL A  25;ALA A  33;PRO A  38;ILE A  51;SER A  55","None;None;EIC A 601 (-3.5A);EIC A 601 (-4.6A);None;None","0.88A","5hbsA-2q9sA:20.0","5hbsA-2q9sA:31.21"]]