SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 7 PHE A  30
VAL A  27
ILE A  22
GLY A  38
 NO3  A 501 (-4.7A)
None
None
None
 0.93A 11gsA-2q9uA:
undetectable		 11gsA-2q9uA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 HIS A  85
ASP A 155
GLY A  88
HIS A 230
ASP A 171
 FEO  A 701 (-3.5A)
None
None
FEO  A 701 ( 3.3A)
FEO  A 701 ( 2.5A)
 1.32A 1a4lD-2q9uA:
undetectable		 1a4lD-2q9uA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 HIS A 230
HIS A  90
GLU A  87
HIS A  85
ASP A 171
 FEO  A 701 ( 3.3A)
FEO  A 701 (-3.3A)
FEO  A 701 (-2.9A)
FEO  A 701 (-3.5A)
FEO  A 701 ( 2.5A)
 1.35A 1a4lD-2q9uA:
undetectable		 1a4lD-2q9uA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 8 ASP A 171
HIS A  85
HIS A  90
HIS A 152
 FEO  A 701 ( 2.5A)
FEO  A 701 (-3.5A)
FEO  A 701 (-3.3A)
FEO  A 701 ( 3.4A)
 0.86A 1ei6D-2q9uA:
undetectable		 1ei6D-2q9uA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 10 ALA A 344
ALA A 312
LEU A 277
LEU A 399
ALA A 395
 None
 1.04A 2bxgB-2q9uA:
undetectable		 2bxgB-2q9uA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 LEU A 263
LEU A 291
LEU A 290
LEU A 278
ALA A 274
 None
 0.98A 2egvB-2q9uA:
undetectable		 2egvB-2q9uA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 ASN A  42
ILE A  22
ALA A 229
ASN A 170
VAL A  27
 None
 1.29A 2gl0A-2q9uA:
undetectable
2gl0C-2q9uA:
undetectable		 2gl0A-2q9uA:
15.68
2gl0C-2q9uA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 9 TYR A 306
TRP A 249
TYR A  33
HIS A  31
GLY A  32
 None
None
None
NO3  A 501 (-3.9A)
None
 1.38A 2ha6B-2q9uA:
1.3		 2ha6B-2q9uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 HIS A  85
ASP A 155
GLY A  88
HIS A 230
ASP A 171
 FEO  A 701 (-3.5A)
None
None
FEO  A 701 ( 3.3A)
FEO  A 701 ( 2.5A)
 1.43A 2pgfA-2q9uA:
undetectable		 2pgfA-2q9uA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 11 ASP A  89
HIS A  90
HIS A 152
ASP A 171
HIS A 230
 FEO  A 701 ( 2.4A)
FEO  A 701 (-3.3A)
FEO  A 701 ( 3.4A)
FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.3A)
 0.88A 2q0jB-2q9uA:
20.3		 2q0jB-2q9uA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 PRO A 324
VAL A 326
THR A 379
ILE A 360
ASP A 359
 NO3  A 502 (-3.7A)
None
None
None
None
 1.34A 2v95A-2q9uA:
undetectable		 2v95A-2q9uA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 ILE A 146
LEU A 167
VAL A 221
GLU A 222
ILE A 243
 None
 1.14A 2vn0A-2q9uA:
undetectable		 2vn0A-2q9uA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 7 LEU A 136
LEU A 143
PHE A 145
LEU A 128
 None
 0.76A 2vq5B-2q9uA:
undetectable		 2vq5B-2q9uA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 6 LEU A 143
PHE A 168
LEU A 167
ASP A 164
 None
 1.07A 2wm3A-2q9uA:
7.8		 2wm3A-2q9uA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 4 VAL A 261
ARG A 272
ILE A 378
THR A 288
 None
 1.38A 3cl9A-2q9uA:
undetectable		 3cl9A-2q9uA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 MET A 239
GLU A 222
ARG A 141
VAL A  17
ILE A  14
 None
 1.48A 3jayA-2q9uA:
undetectable		 3jayA-2q9uA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 6 THR A 157
ASN A  84
CYH A 112
ILE A 129
 None
 1.46A 3w9tB-2q9uA:
undetectable		 3w9tB-2q9uA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		3 / 3 ASP A 164
LEU A 227
VAL A  82
 None
 0.65A 4jecB-2q9uA:
undetectable		 4jecB-2q9uA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 TYR A 332
TYR A  33
GLU A  87
LEU A 204
LEU A 303
 None
None
FEO  A 701 (-2.9A)
None
None
 1.31A 4k36B-2q9uA:
undetectable		 4k36B-2q9uA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 11 TYR A 332
TYR A  33
GLU A  87
LEU A 204
LEU A 303
 None
None
FEO  A 701 (-2.9A)
None
None
 1.34A 4k37B-2q9uA:
undetectable		 4k37B-2q9uA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 TYR A 332
TYR A  33
GLU A  87
LEU A 204
LEU A 303
 None
None
FEO  A 701 (-2.9A)
None
None
 1.31A 4k38B-2q9uA:
undetectable		 4k38B-2q9uA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 TYR A 332
TYR A  33
GLU A  87
LEU A 204
LEU A 303
 None
None
FEO  A 701 (-2.9A)
None
None
 1.40A 4k39A-2q9uA:
undetectable		 4k39A-2q9uA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 7 VAL A 130
ILE A 129
LEU A  94
LEU A 116
 None
 0.78A 4l1wA-2q9uA:
undetectable		 4l1wA-2q9uA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 9 SER A 283
ALA A 276
LEU A 277
GLY A 396
ALA A 329
 None
 1.45A 4l6va-2q9uA:
undetectable
4l6vf-2q9uA:
0.0		 4l6va-2q9uA:
18.68
4l6vf-2q9uA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 9 SER A 283
ALA A 395
LEU A 399
GLY A 400
ALA A 329
 None
 1.26A 4l6va-2q9uA:
undetectable
4l6vf-2q9uA:
0.0		 4l6va-2q9uA:
18.68
4l6vf-2q9uA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 GLY A 174
GLY A 172
ALA A 229
TYR A  33
GLU A 198
 None
 1.15A 4lg1B-2q9uA:
undetectable		 4lg1B-2q9uA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		3 / 3 ASP A  89
VAL A  23
ASN A 170
 FEO  A 701 ( 2.4A)
None
None
 0.78A 4lmnA-2q9uA:
undetectable		 4lmnA-2q9uA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 5 TYR A  44
THR A 200
LEU A 204
THR A 157
 None
 1.46A 4mbsB-2q9uA:
undetectable		 4mbsB-2q9uA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		3 / 3 ARG A 235
GLU A  12
TYR A 225
 None
 0.94A 4r29D-2q9uA:
undetectable		 4r29D-2q9uA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 7 VAL A 130
ILE A 129
LEU A  94
LEU A 116
 None
 0.71A 4xo7A-2q9uA:
undetectable		 4xo7A-2q9uA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 7 ARG A 141
ASP A 164
ILE A 166
TYR A 225
 None
 1.20A 5a06B-2q9uA:
4.4		 5a06B-2q9uA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 7 HIS A 230
GLY A 172
ASN A 170
HIS A 152
 FEO  A 701 ( 3.3A)
None
None
FEO  A 701 ( 3.4A)
 1.23A 5a5zC-2q9uA:
17.3		 5a5zC-2q9uA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 6 ASP A 171
HIS A  90
HIS A 230
HIS A 152
HIS A  31
 FEO  A 701 ( 2.5A)
FEO  A 701 (-3.3A)
FEO  A 701 ( 3.3A)
FEO  A 701 ( 3.4A)
NO3  A 501 (-3.9A)
 1.25A 5ncdA-2q9uA:
undetectable
5ncdD-2q9uA:
undetectable		 5ncdA-2q9uA:
22.38
5ncdD-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 6 ASP A 171
HIS A 152
HIS A  85
HIS A 230
 FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.4A)
FEO  A 701 (-3.5A)
FEO  A 701 ( 3.3A)
 0.95A 5ncdA-2q9uA:
undetectable
5ncdD-2q9uA:
undetectable		 5ncdA-2q9uA:
22.38
5ncdD-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 6 ASP A 171
HIS A 230
HIS A 176
HIS A 152
HIS A  31
 FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.3A)
NO3  A 501 (-4.8A)
FEO  A 701 ( 3.4A)
NO3  A 501 (-3.9A)
 1.38A 5ncdA-2q9uA:
undetectable
5ncdD-2q9uA:
undetectable		 5ncdA-2q9uA:
22.38
5ncdD-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 6 ASP A 171
HIS A 152
HIS A  85
HIS A 230
 FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.4A)
FEO  A 701 (-3.5A)
FEO  A 701 ( 3.3A)
 0.92A 5ncdB-2q9uA:
undetectable
5ncdC-2q9uA:
undetectable		 5ncdB-2q9uA:
22.38
5ncdC-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 6 HIS A  31
ASP A 171
HIS A  90
HIS A 230
HIS A 152
 NO3  A 501 (-3.9A)
FEO  A 701 ( 2.5A)
FEO  A 701 (-3.3A)
FEO  A 701 ( 3.3A)
FEO  A 701 ( 3.4A)
 1.28A 5ncdB-2q9uA:
undetectable
5ncdC-2q9uA:
undetectable		 5ncdB-2q9uA:
22.38
5ncdC-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 6 HIS A  31
ASP A 171
HIS A 230
HIS A 176
HIS A 152
 NO3  A 501 (-3.9A)
FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.3A)
NO3  A 501 (-4.8A)
FEO  A 701 ( 3.4A)
 1.44A 5ncdB-2q9uA:
undetectable
5ncdC-2q9uA:
undetectable		 5ncdB-2q9uA:
22.38
5ncdC-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 8 ASP A 171
HIS A 152
HIS A  85
HIS A 230
 FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.4A)
FEO  A 701 (-3.5A)
FEO  A 701 ( 3.3A)
 0.97A 5nekB-2q9uA:
undetectable		 5nekB-2q9uA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 8 ASP A 171
HIS A 152
HIS A  85
HIS A 230
 FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.4A)
FEO  A 701 (-3.5A)
FEO  A 701 ( 3.3A)
 0.92A 5nekD-2q9uA:
undetectable		 5nekD-2q9uA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 6 ASP A 171
HIS A  90
HIS A 230
HIS A 152
HIS A  31
 FEO  A 701 ( 2.5A)
FEO  A 701 (-3.3A)
FEO  A 701 ( 3.3A)
FEO  A 701 ( 3.4A)
NO3  A 501 (-3.9A)
 1.28A 5nelA-2q9uA:
2.6
5nelD-2q9uA:
undetectable		 5nelA-2q9uA:
22.38
5nelD-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 6 ASP A 171
HIS A 152
HIS A  85
HIS A 230
 FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.4A)
FEO  A 701 (-3.5A)
FEO  A 701 ( 3.3A)
 0.92A 5nelA-2q9uA:
2.6
5nelD-2q9uA:
undetectable		 5nelA-2q9uA:
22.38
5nelD-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 6 ASP A 171
HIS A 230
HIS A 176
HIS A 152
HIS A  31
 FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.3A)
NO3  A 501 (-4.8A)
FEO  A 701 ( 3.4A)
NO3  A 501 (-3.9A)
 1.44A 5nelA-2q9uA:
2.6
5nelD-2q9uA:
undetectable		 5nelA-2q9uA:
22.38
5nelD-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 6 HIS A  31
ASP A 171
HIS A 230
HIS A 176
HIS A 152
 NO3  A 501 (-3.9A)
FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.3A)
NO3  A 501 (-4.8A)
FEO  A 701 ( 3.4A)
 1.45A 5nelB-2q9uA:
undetectable
5nelC-2q9uA:
undetectable		 5nelB-2q9uA:
22.38
5nelC-2q9uA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 6 PHE A 158
PRO A 147
VAL A 148
THR A 109
 None
 1.18A 5t7bA-2q9uA:
3.9		 5t7bA-2q9uA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		5 / 12 ALA A 302
PHE A  30
ALA A  91
ALA A  86
THR A 200
 None
NO3  A 501 (-4.7A)
None
None
None
 1.21A 5tl8A-2q9uA:
undetectable		 5tl8A-2q9uA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 4 VAL A 148
LEU A 215
ASN A 170
ASP A 171
 None
None
None
FEO  A 701 ( 2.5A)
 1.02A 5vcyA-2q9uA:
undetectable		 5vcyA-2q9uA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 5 HIS A  34
HIS A 304
LEU A 290
VAL A 289
 None
 1.09A 6bc9A-2q9uA:
undetectable		 6bc9A-2q9uA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		3 / 3 TYR A  41
HIS A 230
PHE A  30
 None
FEO  A 701 ( 3.3A)
NO3  A 501 (-4.7A)
 0.98A 6esmA-2q9uA:
2.3		 6esmA-2q9uA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 8 TRP A 234
ASP A 171
HIS A 152
GLU A 198
 None
FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.4A)
None
 1.25A 6mn4B-2q9uA:
undetectable		 6mn4B-2q9uA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2q9u A-TYPE FLAVOPROTEIN
(Giardia
intestinalis) 		4 / 8 TRP A 234
ASP A 171
HIS A 152
GLU A 198
 None
FEO  A 701 ( 2.5A)
FEO  A 701 ( 3.4A)
None
 1.19A 6mn4D-2q9uA:
undetectable		 6mn4D-2q9uA:
20.48