SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2q9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 2q9v MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 ILE A 870
MET A 908
LEU A 844
VAL A 917
LEU A 919
 None
 1.26A 2w98A-2q9vA:
undetectable		 2w98A-2q9vA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2q9v MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 GLY A 858
ILE A 855
VAL A 904
VAL A 896
 None
 0.77A 3fi0B-2q9vA:
undetectable		 3fi0B-2q9vA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2q9v MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 MET A 838
SER A 837
LEU A 882
ILE A 867
GLY A 885
 None
 1.26A 6dlzA-2q9vA:
undetectable
6dlzD-2q9vA:
undetectable		 6dlzA-2q9vA:
17.20
6dlzD-2q9vA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2q9v MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 ILE A 867
GLY A 885
MET A 838
SER A 837
LEU A 882
 None
 1.27A 6dlzB-2q9vA:
undetectable
6dlzC-2q9vA:
undetectable		 6dlzB-2q9vA:
17.20
6dlzC-2q9vA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2q9v MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 MET A 838
SER A 837
LEU A 882
ILE A 867
GLY A 885
 None
 1.28A 6dm0B-2q9vA:
undetectable
6dm0C-2q9vA:
undetectable		 6dm0B-2q9vA:
17.20
6dm0C-2q9vA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2q9v MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 MET A 838
SER A 837
LEU A 882
ILE A 867
GLY A 885
 None
 1.26A 6dm1A-2q9vA:
undetectable
6dm1D-2q9vA:
undetectable		 6dm1A-2q9vA:
17.20
6dm1D-2q9vA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2q9v MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 ILE A 867
GLY A 885
MET A 838
SER A 837
LEU A 882
 None
 1.26A 6dm1B-2q9vA:
undetectable
6dm1C-2q9vA:
undetectable		 6dm1B-2q9vA:
17.20
6dm1C-2q9vA:
17.20