SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qar'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qar TELSAM DOMAIN
(Escherichia
coli) 		4 / 7 LYS B  39
GLN B  36
LEU B  84
PHE B  45
 None
 1.04A 2eijP-2qarB:
undetectable
2eijW-2qarB:
1.6		 2eijP-2qarB:
15.87
2eijW-2qarB:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 2qar E80-TELSAM DOMAIN
TELSAM DOMAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 8 LEU A  85
ARG A  73
SER A  98
VAL B  80
 NH4  A 201 (-4.9A)
None
None
None
 1.15A 2qd2A-2qarA:
undetectable		 2qd2A-2qarA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 2qar TELSAM DOMAIN
(Escherichia
coli) 		5 / 12 LEU B  65
MET B  57
TRP B  37
LEU B  38
ILE B  50
 None
 1.38A 2ydoA-2qarB:
undetectable		 2ydoA-2qarB:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qar E80-TELSAM DOMAIN
(Escherichia
coli) 		4 / 7 LYS A  39
GLN A  36
LEU A  84
PHE A  45
 None
 0.98A 2zxwC-2qarA:
undetectable
2zxwJ-2qarA:
undetectable		 2zxwC-2qarA:
20.10
2zxwJ-2qarA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qar TELSAM DOMAIN
(Escherichia
coli) 		4 / 7 LYS B  39
GLN B  36
LEU B  84
PHE B  45
 None
 0.99A 2zxwC-2qarB:
undetectable
2zxwJ-2qarB:
1.6		 2zxwC-2qarB:
15.87
2zxwJ-2qarB:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2qar TELSAM DOMAIN
(Escherichia
coli) 		4 / 6 LYS B  39
GLN B  36
LEU B  84
PHE B  45
 None
 1.27A 6nmpC-2qarB:
undetectable
6nmpJ-2qarB:
1.6		 6nmpC-2qarB:
15.87
6nmpJ-2qarB:
19.39