SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		3 / 3 ASP B  69
LEU B  64
LEU B  65
 None
 0.81A 1np1B-2qb0B:
undetectable		 1np1B-2qb0B:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		5 / 12 ALA B 222
PHE B 246
LEU B 226
ALA B 223
ILE B 171
 None
 0.94A 2aclA-2qb0B:
undetectable
2aclE-2qb0B:
undetectable		 2aclA-2qb0B:
24.05
2aclE-2qb0B:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		5 / 12 TYR B 181
GLN B  91
LEU B 172
VAL B 164
ALA B  92
 None
 1.46A 2g70B-2qb0B:
undetectable		 2g70B-2qb0B:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		4 / 6 SER B  30
ASP B  33
ASP B  32
GLU B 157
 None
MN  B 257 (-2.6A)
None
MN  B 257 (-2.9A)
 1.14A 2j2pE-2qb0B:
undetectable
2j2pF-2qb0B:
undetectable		 2j2pE-2qb0B:
22.58
2j2pF-2qb0B:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		5 / 12 MET B 195
PHE B 207
ALA B 205
PHE B 246
GLY B 170
 None
 1.46A 3aobC-2qb0B:
undetectable		 3aobC-2qb0B:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		5 / 10 ALA B 222
PHE B 246
LEU B 226
ALA B 223
ILE B 171
 None
 1.02A 3falC-2qb0B:
undetectable		 3falC-2qb0B:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		5 / 11 ALA B 222
PHE B 246
LEU B 226
ALA B 223
ILE B 171
 None
 0.97A 3fc6A-2qb0B:
undetectable		 3fc6A-2qb0B:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		3 / 3 GLU B 157
LEU B  24
LEU B  62
 MN  B 257 (-2.9A)
None
None
 0.75A 3ohtA-2qb0B:
undetectable		 3ohtA-2qb0B:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		3 / 3 GLU B 157
LEU B  24
LEU B  62
 MN  B 257 (-2.9A)
None
None
 0.74A 3ohtB-2qb0B:
2.2		 3ohtB-2qb0B:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		4 / 6 ALA B  35
GLN B  36
LEU B  38
LEU B  22
 None
 1.19A 4xoyA-2qb0B:
undetectable		 4xoyA-2qb0B:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		4 / 6 ALA B  35
GLN B  36
LEU B  38
LEU B  22
 None
 1.08A 4xp3A-2qb0B:
undetectable		 4xp3A-2qb0B:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		4 / 7 THR B 119
TYR B 111
GLU B 104
HIS B 124
 None
None
MN  B 256 (-2.8A)
None
 1.06A 5ecnA-2qb0B:
undetectable		 5ecnA-2qb0B:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		5 / 12 THR B  54
GLY B  78
VAL B  80
TRP B  37
PHE B  70
 None
 1.34A 5jo9A-2qb0B:
undetectable		 5jo9A-2qb0B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA
(Escherichia
virus
T4) 		4 / 4 ASP B  32
SER B  30
ASP B  33
HIS B  21
 None
None
MN  B 257 (-2.6A)
MN  B 257 (-3.3A)
 1.31A 5wyqB-2qb0B:
0.0		 5wyqB-2qb0B:
24.28