SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK2_A_T44A3004_1 (SERUM ALBUMIN)	2qc7	ENDOPLASMIC RETICULUM PROTEIN ERP29 (Homo sapiens)	4 / 7	PHE A 118 PHE A 73 ALA A 38 VAL A 91	None	0.89A	1hk2A-2qc7A: undetectable	1hk2A-2qc7A: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_A_ZPCA1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2qc7	ENDOPLASMIC RETICULUM PROTEIN ERP29 (Homo sapiens)	4 / 7	PHE A 46 VAL A 91 ILE A 93 ASN A 101	None	0.98A	4a97E-2qc7A: 2.8	4a97E-2qc7A: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_E_ZPCE1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2qc7	ENDOPLASMIC RETICULUM PROTEIN ERP29 (Homo sapiens)	4 / 8	PHE A 46 VAL A 91 ILE A 93 ASN A 101	None	1.00A	4a97D-2qc7A: 2.7	4a97D-2qc7A: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_H_ZPCH1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2qc7	ENDOPLASMIC RETICULUM PROTEIN ERP29 (Homo sapiens)	4 / 8	PHE A 46 VAL A 91 ILE A 93 ASN A 101	None	0.96A	4a97G-2qc7A: 1.7	4a97G-2qc7A: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_J_ZPCJ1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2qc7	ENDOPLASMIC RETICULUM PROTEIN ERP29 (Homo sapiens)	4 / 8	PHE A 46 VAL A 91 ILE A 93 ASN A 101	None	1.05A	4a97I-2qc7A: 2.8	4a97I-2qc7A: 20.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK2_A_T44A3004_1","SERUM ALBUMIN","2qc7","ENDOPLASMIC RETICULUM PROTEIN ERP29","Homo sapiens",4,"PHE A 118;PHE A  73;ALA A  38;VAL A  91","None","0.89A","1hk2A-2qc7A:undetectable","1hk2A-2qc7A:18.12"],["4A97_A_ZPCA1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","2qc7","ENDOPLASMIC RETICULUM PROTEIN ERP29","Homo sapiens",4,"PHE A  46;VAL A  91;ILE A  93;ASN A 101","None","0.98A","4a97E-2qc7A:2.8","4a97E-2qc7A:20.87"],["4A97_E_ZPCE1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","2qc7","ENDOPLASMIC RETICULUM PROTEIN ERP29","Homo sapiens",4,"PHE A  46;VAL A  91;ILE A  93;ASN A 101","None","1.00A","4a97D-2qc7A:2.7","4a97D-2qc7A:20.87"],["4A97_H_ZPCH1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","2qc7","ENDOPLASMIC RETICULUM PROTEIN ERP29","Homo sapiens",4,"PHE A  46;VAL A  91;ILE A  93;ASN A 101","None","0.96A","4a97G-2qc7A:1.7","4a97G-2qc7A:20.87"],["4A97_J_ZPCJ1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","2qc7","ENDOPLASMIC RETICULUM PROTEIN ERP29","Homo sapiens",4,"PHE A  46;VAL A  91;ILE A  93;ASN A 101","None","1.05A","4a97I-2qc7A:2.8","4a97I-2qc7A:20.87"]]