SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AJV_L_COCL501_1 (ANTIBODY 7A1 FAB')	2qck	FLAVIN REDUCTASE DOMAIN PROTEIN (Arthrobacter sp. FB24)	4 / 7	ALA A 57 ARG A 58 TYR A 30 TYR A 35	None PO4 A 167 (-4.4A) None None	1.07A	2ajvH-2qckA: undetectable 2ajvL-2qckA: undetectable	2ajvH-2qckA: 20.27 2ajvL-2qckA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7W_B_SALB1300_1 (LYSR-TYPE REGULATORY PROTEIN)	2qck	FLAVIN REDUCTASE DOMAIN PROTEIN (Arthrobacter sp. FB24)	5 / 10	ILE A 109 GLY A 103 THR A 27 HIS A 75 ILE A 118	None	1.07A	2y7wB-2qckA: undetectable	2y7wB-2qckA: 23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HB8_A_DXCA75_0 (PPCA)	2qck	FLAVIN REDUCTASE DOMAIN PROTEIN (Arthrobacter sp. FB24)	4 / 8	ILE A 25 LEU A 84 ILE A 109 GLY A 97	None	0.77A	4hb8A-2qckA: undetectable	4hb8A-2qckA: 10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HSW_A_ACTA501_0 (ORF 37)	2qck	FLAVIN REDUCTASE DOMAIN PROTEIN (Arthrobacter sp. FB24)	4 / 5	ARG A 94 SER A 62 SER A 60 SER A 61	None	1.46A	5hswA-2qckA: undetectable	5hswA-2qckA: 17.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AJV_L_COCL501_1","ANTIBODY 7A1 FAB';ANTIBODY 7A1 FAB'","2qck","FLAVIN REDUCTASE DOMAIN PROTEIN","Arthrobacter sp. FB24",4,"ALA A  57;ARG A  58;TYR A  30;TYR A  35","None;PO4 A 167 (-4.4A);None;None","1.07A","2ajvH-2qckA:undetectable;2ajvL-2qckA:undetectable","2ajvH-2qckA:20.27;2ajvL-2qckA:17.84"],["2Y7W_B_SALB1300_1","LYSR-TYPE REGULATORY PROTEIN","2qck","FLAVIN REDUCTASE DOMAIN PROTEIN","Arthrobacter sp. FB24",5,"ILE A 109;GLY A 103;THR A  27;HIS A  75;ILE A 118","None","1.07A","2y7wB-2qckA:undetectable","2y7wB-2qckA:23.50"],["4HB8_A_DXCA75_0","PPCA","2qck","FLAVIN REDUCTASE DOMAIN PROTEIN","Arthrobacter sp. FB24",4,"ILE A  25;LEU A  84;ILE A 109;GLY A  97","None","0.77A","4hb8A-2qckA:undetectable","4hb8A-2qckA:10.78"],["5HSW_A_ACTA501_0","ORF 37","2qck","FLAVIN REDUCTASE DOMAIN PROTEIN","Arthrobacter sp. FB24",4,"ARG A  94;SER A  62;SER A  60;SER A  61","None","1.46A","5hswA-2qckA:undetectable","5hswA-2qckA:17.24"]]