SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 2qco CMER
(Campylobacter
jejuni) 		5 / 12 ILE A  40
LEU A  36
GLU A  58
ILE A  39
ILE A  18
 None
 1.22A 2gj5A-2qcoA:
undetectable		 2gj5A-2qcoA:
22.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGG_A_CHDA211_0
(CMER)		 2qco CMER
(Campylobacter
jejuni) 		6 / 7 CYH A  69
PHE A  99
PHE A 103
PHE A 137
SER A 138
TYR A 139
 None
GOL  A 301 (-4.7A)
GOL  A 301 (-4.7A)
None
GOL  A 301 (-2.9A)
GOL  A 301 (-4.6A)
 0.39A 3hggA-2qcoA:
30.3		 3hggA-2qcoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGG_A_CHDA211_0
(CMER)		 2qco CMER
(Campylobacter
jejuni) 		4 / 7 CYH A  69
PHE A 103
PHE A 137
LYS A 170
 None
GOL  A 301 (-4.7A)
None
GOL  A 301 ( 4.7A)
 0.82A 3hggA-2qcoA:
30.3		 3hggA-2qcoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QPS_A_CHDA211_0
(CMER)		 2qco CMER
(Campylobacter
jejuni) 		9 / 10 LEU A  65
PHE A 103
ALA A 108
PHE A 111
GLY A 112
ILE A 115
TRP A 129
PHE A 137
CYH A 166
 None
GOL  A 301 (-4.7A)
None
None
None
None
None
None
GOL  A 301 (-4.0A)
 0.63A 3qpsA-2qcoA:
30.0		 3qpsA-2qcoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QPS_A_CHDA211_0
(CMER)		 2qco CMER
(Campylobacter
jejuni) 		9 / 10 LEU A  65
PHE A 103
ALA A 108
PHE A 111
GLY A 112
ILE A 115
TRP A 129
PHE A 137
LYS A 170
 None
GOL  A 301 (-4.7A)
None
None
None
None
None
None
GOL  A 301 ( 4.7A)
 0.63A 3qpsA-2qcoA:
30.0		 3qpsA-2qcoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qco CMER
(Campylobacter
jejuni) 		5 / 12 VAL A 194
PHE A  95
SER A  94
PHE A 145
VAL A 198
 None
 1.14A 4kyaB-2qcoA:
undetectable		 4kyaB-2qcoA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qco CMER
(Campylobacter
jejuni) 		5 / 12 VAL A 194
PHE A  95
SER A  94
PHE A 145
VAL A 198
 None
 1.12A 4kyaD-2qcoA:
undetectable		 4kyaD-2qcoA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qco CMER
(Campylobacter
jejuni) 		5 / 12 VAL A 194
PHE A  95
SER A  94
PHE A 145
VAL A 198
 None
 1.11A 4kyaF-2qcoA:
undetectable		 4kyaF-2qcoA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qco CMER
(Campylobacter
jejuni) 		5 / 12 VAL A 194
PHE A  95
SER A  94
PHE A 145
VAL A 198
 None
 1.15A 4kyaH-2qcoA:
undetectable		 4kyaH-2qcoA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2qco CMER
(Campylobacter
jejuni) 		3 / 3 ASP A  66
LEU A  65
PHE A  62
 None
 0.75A 4pthA-2qcoA:
undetectable		 4pthA-2qcoA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 2qco CMER
(Campylobacter
jejuni) 		5 / 12 PHE A  62
ILE A 130
GLN A 118
TYR A 116
VAL A 178
 None
 1.16A 4qzuC-2qcoA:
undetectable		 4qzuC-2qcoA:
18.78