SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qcz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 12 VAL A 258
LEU A 226
SER A 228
LEU A 231
THR A 243
 None
 1.07A 1kw0A-2qczA:
undetectable		 1kw0A-2qczA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 11 VAL A 258
LEU A 226
SER A 228
LEU A 231
THR A 243
 None
 1.17A 1mmtA-2qczA:
undetectable		 1mmtA-2qczA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		3 / 3 GLN A 178
ILE A 254
TYR A 255
 None
 0.51A 1vifA-2qczA:
undetectable		 1vifA-2qczA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		3 / 3 THR A 225
LYS A 310
GLU A 224
 None
 0.97A 3ijdB-2qczA:
undetectable		 3ijdB-2qczA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		4 / 4 GLY A 263
GLU A 262
ASP A 241
ASP A 264
 None
 1.33A 3mb5A-2qczA:
undetectable		 3mb5A-2qczA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		4 / 6 PHE A  31
ALA A  42
PRO A  47
LEU A  66
 None
 1.11A 4dtzB-2qczA:
undetectable		 4dtzB-2qczA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 7 PHE A 197
THR A 243
ASP A 222
ILE A 180
VAL A 256
 None
 1.44A 5ik1A-2qczA:
undetectable		 5ik1A-2qczA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qcz OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 12 GLY A 221
ILE A 328
GLY A 263
THR A 261
THR A 225
 None
 1.17A 6e8qA-2qczA:
undetectable		 6e8qA-2qczA:
13.73