SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 7 GLY A  46
TYR A  35
ALA A 108
GLU A  49
 None
 0.77A 1dmaA-2qddA:
undetectable		 1dmaA-2qddA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		3 / 3 ASP A  39
ARG A  37
ASP A 368
 None
 0.84A 1vptA-2qddA:
undetectable		 1vptA-2qddA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 5 LEU A 125
ALA A 309
LEU A 305
MET A 107
 None
 1.22A 2oaxA-2qddA:
undetectable		 2oaxA-2qddA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 7 ILE A  69
PRO A 355
GLY A  46
TRP A  47
 None
 1.20A 2pnjB-2qddA:
3.8		 2pnjB-2qddA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 9 TRP A 110
SER A 347
TRP A 122
LEU A 121
GLY A 350
 None
 1.48A 2wscA-2qddA:
undetectable		 2wscA-2qddA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 9 TRP A 110
SER A 347
TRP A 122
LEU A 121
GLY A 350
 None
 1.48A 2wseA-2qddA:
0.0		 2wseA-2qddA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 9 TRP A 110
SER A 347
TRP A 122
LEU A 121
GLY A 350
 None
 1.48A 2wsfA-2qddA:
undetectable		 2wsfA-2qddA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 8 LEU A   6
ILE A   3
LEU A  76
LEU A  36
 None
 0.80A 2xfhA-2qddA:
undetectable		 2xfhA-2qddA:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		3 / 3 PRO A 132
LEU A 342
ARG A 160
 None
 0.89A 3aqiA-2qddA:
3.8		 3aqiA-2qddA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 4 LEU A  13
PRO A  14
LEU A 326
ARG A 337
 None
 1.29A 3hcoA-2qddA:
3.7		 3hcoA-2qddA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		3 / 3 CYH A  51
PRO A  63
ASP A  12
 None
 0.95A 3hlwB-2qddA:
undetectable		 3hlwB-2qddA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gB-2qddA:
1.7		 3j6gB-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gD-2qddA:
1.4		 3j6gD-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gF-2qddA:
1.6		 3j6gF-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gH-2qddA:
1.3		 3j6gH-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gJ-2qddA:
1.5		 3j6gJ-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gL-2qddA:
2.4		 3j6gL-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gN-2qddA:
1.4		 3j6gN-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gP-2qddA:
1.4		 3j6gP-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 10 VAL A 262
ASP A 241
HIS A 250
THR A 273
LEU A 307
 None
 1.42A 3j6gR-2qddA:
1.4		 3j6gR-2qddA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 9 TRP A 110
SER A 347
TRP A 122
LEU A 121
GLY A 350
 None
 1.38A 3lw5A-2qddA:
undetectable		 3lw5A-2qddA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 6 GLY A 296
THR A 297
LEU A 299
ASP A 293
 None
 1.04A 3ps9A-2qddA:
undetectable		 3ps9A-2qddA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 8 ALA A 343
ILE A 135
ALA A 308
ALA A 309
 None
 0.63A 3r9tA-2qddA:
3.7		 3r9tA-2qddA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 12 ALA A 309
HIS A 306
LEU A 307
GLY A 126
PRO A 312
 None
 1.28A 3tm4A-2qddA:
2.0		 3tm4A-2qddA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 12 ALA A 309
HIS A 306
LEU A 307
GLY A 126
PRO A 312
 None
 1.25A 3tm4B-2qddA:
2.2		 3tm4B-2qddA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 6 GLY A  46
TYR A  35
ALA A 108
GLU A  49
 None
 0.96A 4ae1A-2qddA:
undetectable		 4ae1A-2qddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		3 / 3 LEU A  13
PRO A  14
ARG A 337
 None
 0.67A 4klrB-2qddA:
3.7		 4klrB-2qddA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		3 / 3 CYH A  51
PRO A  63
ASP A  12
 None
 0.99A 4pm5A-2qddA:
undetectable		 4pm5A-2qddA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 6 ARG A 274
ILE A 278
GLN A 277
ASP A  85
 None
 1.20A 4z4dA-2qddA:
undetectable		 4z4dA-2qddA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		5 / 11 PRO A 312
MET A 289
ILE A 264
LEU A 272
THR A 273
 None
 1.39A 5tiyA-2qddA:
undetectable		 5tiyA-2qddA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 8 TYR A  57
GLU A 242
TRP A  53
ASN A 196
 None
 1.23A 6c71B-2qddA:
undetectable		 6c71B-2qddA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Roseovarius
nubinhibens) 		4 / 7 ARG A 268
TYR A  57
GLU A 242
CYH A 227
 None
 1.36A 6mn5E-2qddA:
undetectable		 6mn5E-2qddA:
12.23