SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		3 / 3 LEU A  64
PHE A 115
ARG A  73
 None
 0.63A 1xdkB-2qdjA:
2.6		 1xdkB-2qdjA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		3 / 3 LEU A  64
PHE A 115
ARG A  73
 None
 0.63A 1xdkF-2qdjA:
2.5		 1xdkF-2qdjA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		4 / 6 PHE A 299
TYR A 321
GLY A 203
LYS A 202
 None
 1.50A 2i30A-2qdjA:
1.5		 2i30A-2qdjA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		3 / 3 SER A 350
ARG A 355
GLN A 354
 None
 0.83A 2xnrA-2qdjA:
undetectable		 2xnrA-2qdjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		3 / 3 PRO A  67
PHE A 115
ALA A 107
 None
 0.56A 3itaD-2qdjA:
undetectable		 3itaD-2qdjA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		4 / 6 GLY A 100
LEU A 120
ASN A 123
GLU A 125
 None
 0.75A 3zqtA-2qdjA:
undetectable		 3zqtA-2qdjA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 223
ILE A 227
LEU A 277
GLU A 280
 None
 0.96A 4w5nA-2qdjA:
undetectable		 4w5nA-2qdjA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		4 / 5 ASP A 111
PRO A  67
GLU A  72
ARG A  73
 None
 1.49A 5uxcA-2qdjA:
1.1		 5uxcA-2qdjA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 158
PHE A 159
PHE A 336
LEU A 331
 None
 1.08A 5x1bP-2qdjA:
undetectable		 5x1bP-2qdjA:
21.12