SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qdl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		4 / 6 LEU A 141
GLU A  87
ALA A  93
LEU A 144
 None
 1.22A 1etb2-2qdlA:
undetectable		 1etb2-2qdlA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.89A 1hxbB-2qdlA:
undetectable		 1hxbB-2qdlA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 10 ALA A 123
ASP A 121
PHE A  70
ILE A  64
ILE A 139
 None
 1.33A 1j3jA-2qdlA:
undetectable		 1j3jA-2qdlA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 9 ALA A 123
ASP A 121
PHE A  70
ILE A  64
ILE A 139
 None
 1.36A 1j3jB-2qdlA:
undetectable		 1j3jB-2qdlA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 9 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.95A 1ohrB-2qdlA:
undetectable		 1ohrB-2qdlA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 11 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.91A 1t3rB-2qdlA:
undetectable		 1t3rB-2qdlA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.91A 2f80B-2qdlA:
undetectable		 2f80B-2qdlA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.95A 2f81A-2qdlA:
undetectable		 2f81A-2qdlA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A 144
GLY A  94
ALA A  93
VAL A  31
ILE A  88
 None
 0.88A 2f8gA-2qdlA:
undetectable		 2f8gA-2qdlA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 9 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.85A 2o4pB-2qdlA:
undetectable		 2o4pB-2qdlA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		4 / 6 LEU A  95
ILE A  88
ARG A  69
ILE A  64
 None
 0.80A 2q8hA-2qdlA:
undetectable		 2q8hA-2qdlA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.96A 2qakB-2qdlA:
undetectable		 2qakB-2qdlA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.96A 2r5pA-2qdlA:
undetectable		 2r5pA-2qdlA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.96A 2r5pC-2qdlA:
undetectable		 2r5pC-2qdlA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.90A 3bvbB-2qdlA:
undetectable		 3bvbB-2qdlA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.92A 3d20A-2qdlA:
undetectable		 3d20A-2qdlA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.87A 3d20B-2qdlA:
undetectable		 3d20B-2qdlA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.92A 3jvyB-2qdlA:
undetectable		 3jvyB-2qdlA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.83A 3k4vC-2qdlA:
undetectable		 3k4vC-2qdlA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.89A 3ndtD-2qdlA:
undetectable		 3ndtD-2qdlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.83A 3nduC-2qdlA:
undetectable		 3nduC-2qdlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A 144
GLY A  94
ALA A  93
VAL A  31
ILE A  88
 None
 0.88A 3nu5A-2qdlA:
undetectable		 3nu5A-2qdlA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A 144
GLY A  94
ALA A  93
VAL A  31
ILE A  88
 None
 0.89A 3nu5B-2qdlA:
undetectable		 3nu5B-2qdlA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 9 LEU A 144
GLY A  94
ALA A  93
VAL A  31
ILE A  88
 None
 0.87A 3oxvA-2qdlA:
undetectable		 3oxvA-2qdlA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 9 LEU A 144
GLY A  94
ALA A  93
VAL A  31
ILE A  88
 None
 0.89A 3oxvC-2qdlA:
undetectable		 3oxvC-2qdlA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A 144
GLY A  94
ALA A  93
VAL A  31
ILE A  88
 None
 0.82A 3oxxA-2qdlA:
undetectable		 3oxxA-2qdlA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 11 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.85A 3oy4A-2qdlA:
undetectable		 3oy4A-2qdlA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.85A 3pwrB-2qdlA:
undetectable		 3pwrB-2qdlA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 10 ALA A 123
ASP A 121
PHE A  70
ILE A  64
ILE A 139
 None
 1.32A 3qgtA-2qdlA:
undetectable		 3qgtA-2qdlA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.93A 3tkgD-2qdlA:
undetectable		 3tkgD-2qdlA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 VAL A  31
ILE A  84
GLU A 126
ILE A 111
VAL A 100
 None
None
None
None
GOL  A 166 ( 4.1A)
 1.09A 4a97B-2qdlA:
undetectable
4a97C-2qdlA:
undetectable		 4a97B-2qdlA:
18.77
4a97C-2qdlA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 11 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.94A 4dqhA-2qdlA:
undetectable		 4dqhA-2qdlA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 11 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.84A 4qgiB-2qdlA:
undetectable		 4qgiB-2qdlA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		6 / 12 GLY A  94
ILE A  88
VAL A  86
ILE A  96
LEU A  95
LEU A  26
 None
 1.41A 5wy0A-2qdlA:
undetectable		 5wy0A-2qdlA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.96A 6dgxB-2qdlA:
undetectable		 6dgxB-2qdlA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.90A 6difB-2qdlA:
undetectable		 6difB-2qdlA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN
(Caldanaerobacter
subterraneus) 		5 / 12 LEU A  95
VAL A  34
ILE A  14
VAL A  86
ILE A  84
 None
GOL  A 166 ( 4.5A)
None
None
None
 0.84A 6dilB-2qdlA:
undetectable		 6dilB-2qdlA:
19.87