SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		3 / 3 PHE A 280
TRP A 261
GLU A 239
 UNL  A 303 ( 4.7A)
UNL  A 303 (-3.1A)
UNL  A 303 ( 4.1A)
 1.03A 1mogA-2qdrA:
1.2		 1mogA-2qdrA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		3 / 3 HIS A  86
ASP A 285
ASN A 214
 None
 0.63A 1wg8B-2qdrA:
undetectable		 1wg8B-2qdrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 7 PHE A  55
TYR A 260
GLN A  53
TYR A 262
 None
 1.31A 4grqA-2qdrA:
undetectable
4grqC-2qdrA:
undetectable		 4grqA-2qdrA:
17.69
4grqC-2qdrA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 4 ILE A 142
SER A 105
ASP A 173
ASP A 176
 None
 1.40A 4krhB-2qdrA:
undetectable		 4krhB-2qdrA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 8 TYR A 133
ASP A 111
VAL A 218
GLY A 217
 None
 0.90A 5nzyA-2qdrA:
undetectable		 5nzyA-2qdrA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 5 PRO A 236
VAL A 294
GLY A 241
VAL A 284
 None
 1.08A 6ak3B-2qdrA:
undetectable		 6ak3B-2qdrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 4 VAL A 284
GLY A 217
ASP A 212
ASP A 287
 None
 1.30A 6cjkC-2qdrA:
undetectable		 6cjkC-2qdrA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 5 GLY A  32
ASN A 214
ARG A  33
ARG A  31
 None
 1.27A 6dwdB-2qdrA:
undetectable
6dwdD-2qdrA:
undetectable		 6dwdB-2qdrA:
19.73
6dwdD-2qdrA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 5 ARG A  33
ARG A  31
GLY A  32
ASN A 214
 None
 1.27A 6dwjB-2qdrA:
undetectable
6dwjD-2qdrA:
undetectable		 6dwjB-2qdrA:
19.73
6dwjD-2qdrA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 2qdr UNCHARACTERIZED
PROTEIN
(Nostoc
punctiforme) 		4 / 6 GLU A 102
LYS A 146
PHE A 101
PRO A  98
 None
 1.46A 6fgdA-2qdrA:
undetectable		 6fgdA-2qdrA:
23.13