SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qe7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 5 SER D 292
ALA D 229
ASP D 234
GLU D 230
 None
 1.35A 1lqtA-2qe7D:
undetectable
1lqtB-2qe7D:
undetectable		 1lqtA-2qe7D:
23.63
1lqtB-2qe7D:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 5 SER D 292
ALA D 229
ASP D 234
GLU D 230
 None
 1.34A 1lquA-2qe7D:
undetectable
1lquB-2qe7D:
undetectable		 1lquA-2qe7D:
23.63
1lquB-2qe7D:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		5 / 12 PHE D 250
THR D 314
ILE D 296
ILE D 299
ALA D 222
 None
 1.06A 1nv8B-2qe7D:
2.9		 1nv8B-2qe7D:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		5 / 12 GLY D   4
ALA D  70
VAL D  42
ALA D  44
ILE D  30
 None
 0.88A 1rl8A-2qe7D:
undetectable		 1rl8A-2qe7D:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 5 ALA D  75
ASN D  28
ILE D  30
ASP D  72
 None
 1.12A 1yc2D-2qe7D:
undetectable		 1yc2D-2qe7D:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 5 ALA D  75
ASN D  28
ILE D  30
ASP D  72
 None
 1.04A 2h4jA-2qe7D:
undetectable		 2h4jA-2qe7D:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		5 / 12 GLY D 418
GLY D 415
ASP D 136
ILE D 132
LEU D 164
 None
 1.09A 2hmyB-2qe7D:
undetectable		 2hmyB-2qe7D:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		5 / 12 LEU D  93
LEU D  40
ALA D  59
HIS D 112
ILE D 111
 None
 1.12A 2jn3A-2qe7D:
undetectable		 2jn3A-2qe7D:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 8 GLY D 151
GLU D 325
ASN D 323
ALA D 298
 None
 0.93A 3aodA-2qe7D:
undetectable		 3aodA-2qe7D:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 4 GLU D 163
GLY D 131
THR D 130
GLU D 129
 None
 1.13A 3e9xA-2qe7D:
undetectable		 3e9xA-2qe7D:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 8 VAL D 177
VAL D  81
ILE D 285
GLY D 225
 None
 0.93A 3hjoA-2qe7D:
undetectable		 3hjoA-2qe7D:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		3 / 3 SER D 287
ASP D 239
ASP D 125
 None
 0.92A 3iv6C-2qe7D:
2.7		 3iv6C-2qe7D:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		3 / 3 ASP D 319
GLU D 283
SER D 348
 None
 0.82A 3p2kA-2qe7D:
2.5		 3p2kA-2qe7D:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		3 / 4 SER D 342
GLY D 156
GLU D 187
 None
 0.68A 3raeA-2qe7D:
undetectable
3raeC-2qe7D:
undetectable		 3raeA-2qe7D:
21.58
3raeC-2qe7D:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		3 / 3 GLY D 154
GLY D 156
THR D 158
 None
 0.42A 3si7B-2qe7D:
5.6		 3si7B-2qe7D:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 5 PRO D 339
ASP D 338
ILE D 333
VAL D 155
 None
 1.31A 4hytA-2qe7D:
undetectable		 4hytA-2qe7D:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 5 VAL D 103
GLY D  87
ARG D  88
PHE D  90
 None
 0.98A 5d4nA-2qe7D:
undetectable
5d4nC-2qe7D:
undetectable		 5d4nA-2qe7D:
15.23
5d4nC-2qe7D:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		5 / 12 LEU D 260
ILE D  77
THR D  61
ALA D  59
LEU D  93
 None
 1.32A 5ienA-2qe7D:
undetectable		 5ienA-2qe7D:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 7 GLY D  94
GLU D  95
ASP D  98
PHE D  90
 None
 0.97A 5mvsA-2qe7D:
undetectable		 5mvsA-2qe7D:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 6 LEU D 226
THR D 314
LEU D 242
LEU D 128
 None
 0.94A 5tudD-2qe7D:
undetectable		 5tudD-2qe7D:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		5 / 12 LEU D  68
ILE D   6
VAL D  42
CYH D  55
ASP D  62
 None
 1.31A 5vlmG-2qe7D:
undetectable		 5vlmG-2qe7D:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		5 / 7 ILE D  16
VAL D  42
PRO D  24
ILE D  32
THR D  39
 None
 1.15A 6cduF-2qe7D:
undetectable
6cduG-2qe7D:
undetectable		 6cduF-2qe7D:
22.34
6cduG-2qe7D:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2qe7 ATP SYNTHASE SUBUNIT
BETA
(Bacillus
sp.
TA2.A1) 		4 / 7 VAL D 240
ILE D 285
GLY D 182
ALA D 179
 None
 0.88A 6hd6B-2qe7D:
undetectable		 6hd6B-2qe7D:
10.61