SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2qf5	CELL SHAPE DETERMINING PROTEIN MREC (Streptococcus pneumoniae)	3 / 3	SER A 186 GLY A 185 GLN A 183	None	0.48A	3v4tH-2qf5A: undetectable	3v4tH-2qf5A: 20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BPH_B_ACTB404_0 (D-ALANINE--D-ALANINE LIGASE)	2qf5	CELL SHAPE DETERMINING PROTEIN MREC (Streptococcus pneumoniae)	4 / 7	LYS A 181 TYR A 190 GLY A 224 SER A 179	None	1.04A	5bphB-2qf5A: undetectable	5bphB-2qf5A: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IL1_A_SAMA601_1 (METTL3)	2qf5	CELL SHAPE DETERMINING PROTEIN MREC (Streptococcus pneumoniae)	4 / 4	ASP A 201 HIS A 261 ASN A 171 GLN A 128	None	1.26A	5il1A-2qf5A: 0.0	5il1A-2qf5A: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODI_A_ACTA701_0 (HETERODISULFIDE REDUCTASE, SUBUNIT A)	2qf5	CELL SHAPE DETERMINING PROTEIN MREC (Streptococcus pneumoniae)	3 / 3	LYS A 127 LYS A 158 SER A 157	None	1.43A	5odiA-2qf5A: undetectable	5odiA-2qf5A: 13.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3V4T_H_ACTH502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2qf5","CELL SHAPE DETERMINING PROTEIN MREC","Streptococcus pneumoniae",3,"SER A 186;GLY A 185;GLN A 183","None","0.48A","3v4tH-2qf5A:undetectable","3v4tH-2qf5A:20.10"],["5BPH_B_ACTB404_0","D-ALANINE--D-ALANINE LIGASE","2qf5","CELL SHAPE DETERMINING PROTEIN MREC","Streptococcus pneumoniae",4,"LYS A 181;TYR A 190;GLY A 224;SER A 179","None","1.04A","5bphB-2qf5A:undetectable","5bphB-2qf5A:19.59"],["5IL1_A_SAMA601_1","METTL3","2qf5","CELL SHAPE DETERMINING PROTEIN MREC","Streptococcus pneumoniae",4,"ASP A 201;HIS A 261;ASN A 171;GLN A 128","None","1.26A","5il1A-2qf5A:0.0","5il1A-2qf5A:23.38"],["5ODI_A_ACTA701_0","HETERODISULFIDE REDUCTASE, SUBUNIT A","2qf5","CELL SHAPE DETERMINING PROTEIN MREC","Streptococcus pneumoniae",3,"LYS A 127;LYS A 158;SER A 157","None","1.43A","5odiA-2qf5A:undetectable","5odiA-2qf5A:13.76"]]