SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qfc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		5 / 9 VAL A 121
LEU A 142
ILE A 161
ALA A 160
GLU A 158
 None
 0.99A 3mdvA-2qfcA:
undetectable		 3mdvA-2qfcA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		5 / 12 VAL A 121
LEU A 142
ILE A 161
ALA A 160
GLU A 158
 None
 1.00A 3mdvB-2qfcA:
undetectable		 3mdvB-2qfcA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		4 / 7 ILE A 135
ASP A 176
LEU A 177
GLY A 174
 None
 0.81A 4iqqB-2qfcA:
undetectable		 4iqqB-2qfcA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		4 / 8 ILE A 135
ASP A 176
LEU A 177
GLY A 174
 None
 0.85A 4iqqD-2qfcA:
undetectable		 4iqqD-2qfcA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		3 / 3 LYS A 172
ASN A 163
ASP A 209
 None
 0.85A 4o1eA-2qfcA:
undetectable		 4o1eA-2qfcA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		4 / 8 ILE A 225
VAL A 196
TYR A 239
ILE A 235
 None
 0.85A 5mzrE-2qfcA:
3.6		 5mzrE-2qfcA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		4 / 7 ILE A 135
ASP A 176
LEU A 177
GLY A 174
 None
 0.88A 5nooB-2qfcA:
undetectable		 5nooB-2qfcA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		4 / 8 ILE A 135
ASP A 176
LEU A 177
GLY A 174
 None
 0.91A 5nooD-2qfcA:
undetectable		 5nooD-2qfcA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		4 / 6 ILE A 135
ASP A 176
LEU A 177
GLY A 174
 None
 0.96A 5x5qE-2qfcA:
undetectable		 5x5qE-2qfcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		3 / 3 TYR A  64
ALA A  53
LEU A  49
 None
 0.64A 6d9kF-2qfcA:
undetectable		 6d9kF-2qfcA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 2qfc PLCR PROTEIN
(Bacillus
thuringiensis) 		5 / 12 VAL A 196
ASP A 195
ALA A 233
SER A 231
GLN A 118
 None
 1.23A 6ew0F-2qfcA:
undetectable		 6ew0F-2qfcA:
15.38