SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 276
THR A 107
HIS A 134
SER A 198
 None
 0.78A 1c9sT-2qfvA:
0.0
1c9sU-2qfvA:
0.0		 1c9sT-2qfvA:
11.53
1c9sU-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 4 THR A 394
LEU A 398
VAL A 401
LEU A 405
 None
 0.88A 1fbmD-2qfvA:
undetectable		 1fbmD-2qfvA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 276
THR A 107
HIS A 134
SER A 198
 None
 0.88A 1gtfL-2qfvA:
undetectable
1gtfM-2qfvA:
undetectable		 1gtfL-2qfvA:
11.53
1gtfM-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 276
THR A 107
HIS A 134
SER A 198
 None
 0.88A 1gtfN-2qfvA:
0.0
1gtfO-2qfvA:
0.0		 1gtfN-2qfvA:
11.53
1gtfO-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.34A 1gtfO-2qfvA:
0.0
1gtfP-2qfvA:
0.0		 1gtfO-2qfvA:
11.53
1gtfP-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 SER A 198
GLY A 276
THR A 107
HIS A 134
ILE A 131
 None
 1.36A 1gtfL-2qfvA:
undetectable
1gtfV-2qfvA:
undetectable		 1gtfL-2qfvA:
11.53
1gtfV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 7 GLY A  69
THR A 299
THR A 304
ILE A  65
 None
 0.98A 1gtnF-2qfvA:
undetectable
1gtnG-2qfvA:
undetectable		 1gtnF-2qfvA:
11.53
1gtnG-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 7 GLY A  69
THR A 299
THR A 304
ILE A  65
 None
 0.99A 1gtnJ-2qfvA:
undetectable
1gtnK-2qfvA:
undetectable		 1gtnJ-2qfvA:
11.53
1gtnK-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.29A 1gtnR-2qfvA:
0.0
1gtnS-2qfvA:
undetectable		 1gtnR-2qfvA:
11.53
1gtnS-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 196
ALA A 195
PHE A 194
GLY A 193
 None
 1.16A 1mjoD-2qfvA:
undetectable		 1mjoD-2qfvA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 4 THR A 394
LEU A 398
VAL A 401
LEU A 405
 None
 0.76A 1mz9D-2qfvA:
undetectable		 1mz9D-2qfvA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 SER A 239
PHE A 241
ALA A 202
LEU A 209
 None
 0.95A 2bxkA-2qfvA:
undetectable		 2bxkA-2qfvA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 TYR A  68
ILE A  65
ALA A  64
GLU A 306
ILE A  72
 None
 1.05A 2dm6A-2qfvA:
undetectable
2dm6B-2qfvA:
undetectable		 2dm6A-2qfvA:
22.53
2dm6B-2qfvA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 194
GLY A 132
PHE A 199
GLY A 193
VAL A 232
 None
 1.44A 2fqyA-2qfvA:
3.5		 2fqyA-2qfvA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  32
ILE A  27
LEU A 361
VAL A 401
ILE A 409
 None
 0.96A 2nnhA-2qfvA:
undetectable		 2nnhA-2qfvA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  32
ILE A  27
LEU A 361
VAL A 401
ILE A 409
 None
 1.01A 2nnhB-2qfvA:
undetectable		 2nnhB-2qfvA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 ARG A  21
ASP A  44
LEU A  45
GLY A  16
 None
 0.92A 2qqdB-2qfvA:
undetectable
2qqdC-2qfvA:
undetectable		 2qqdB-2qfvA:
15.59
2qqdC-2qfvA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_A_PXLA313_1
(PYRIDOXAL KINASE)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 4 SER A 331
HIS A 317
THR A 327
VAL A 314
 None
NAP  A1001 (-3.8A)
None
NAP  A1001 ( 3.6A)
 1.31A 3fhxA-2qfvA:
3.1		 3fhxA-2qfvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 138
TYR A 274
ASP A 275
LYS A 272
 None
 1.44A 3pocB-2qfvA:
undetectable		 3pocB-2qfvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 405
ILE A 409
PRO A  34
LEU A  36
 None
 1.15A 5eb3A-2qfvA:
undetectable		 5eb3A-2qfvA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5eeuP-2qfvA:
0.0
5eeuQ-2qfvA:
0.0		 5eeuP-2qfvA:
11.53
5eeuQ-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5eeuU-2qfvA:
0.0
5eeuV-2qfvA:
0.0		 5eeuU-2qfvA:
11.53
5eeuV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 SER A 198
GLY A 276
THR A 107
HIS A 134
 None
 0.88A 5eevL-2qfvA:
undetectable
5eevV-2qfvA:
0.0		 5eevL-2qfvA:
11.53
5eevV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.34A 5eevP-2qfvA:
undetectable
5eevQ-2qfvA:
undetectable		 5eevP-2qfvA:
11.53
5eevQ-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5eevU-2qfvA:
undetectable
5eevV-2qfvA:
undetectable		 5eevU-2qfvA:
11.53
5eevV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 SER A 198
GLY A 276
THR A 107
HIS A 134
 None
 0.88A 5eewL-2qfvA:
undetectable
5eewV-2qfvA:
0.0		 5eewL-2qfvA:
11.53
5eewV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5eewP-2qfvA:
undetectable
5eewQ-2qfvA:
0.0		 5eewP-2qfvA:
11.53
5eewQ-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5eewU-2qfvA:
0.0
5eewV-2qfvA:
0.0		 5eewU-2qfvA:
11.53
5eewV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5eexP-2qfvA:
undetectable
5eexQ-2qfvA:
0.0		 5eexP-2qfvA:
11.53
5eexQ-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5eexU-2qfvA:
0.0
5eexV-2qfvA:
0.0		 5eexU-2qfvA:
11.53
5eexV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5eeyP-2qfvA:
0.0
5eeyQ-2qfvA:
0.0		 5eeyP-2qfvA:
11.53
5eeyQ-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5eeyU-2qfvA:
undetectable
5eeyV-2qfvA:
undetectable		 5eeyU-2qfvA:
11.53
5eeyV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 SER A 198
GLY A 276
THR A 107
HIS A 134
 None
 0.88A 5eezL-2qfvA:
0.0
5eezV-2qfvA:
0.0		 5eezL-2qfvA:
11.53
5eezV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5eezP-2qfvA:
0.0
5eezQ-2qfvA:
0.0		 5eezP-2qfvA:
11.53
5eezQ-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5eezU-2qfvA:
undetectable
5eezV-2qfvA:
undetectable		 5eezU-2qfvA:
11.53
5eezV-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5ef0P-2qfvA:
0.0
5ef0Q-2qfvA:
0.0		 5ef0P-2qfvA:
11.53
5ef0Q-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5ef0U-2qfvA:
undetectable
5ef0V-2qfvA:
undetectable		 5ef0U-2qfvA:
11.53
5ef0V-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 SER A 198
GLY A 276
THR A 107
HIS A 134
 None
 0.88A 5ef1L-2qfvA:
0.0
5ef1V-2qfvA:
0.0		 5ef1L-2qfvA:
11.53
5ef1V-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5ef1P-2qfvA:
0.0
5ef1Q-2qfvA:
0.0		 5ef1P-2qfvA:
11.53
5ef1Q-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5ef1U-2qfvA:
undetectable
5ef1V-2qfvA:
undetectable		 5ef1U-2qfvA:
11.53
5ef1V-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 SER A 198
GLY A 276
THR A 107
HIS A 134
 None
 0.88A 5ef2L-2qfvA:
0.0
5ef2V-2qfvA:
undetectable		 5ef2L-2qfvA:
11.53
5ef2V-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5ef2P-2qfvA:
0.0
5ef2Q-2qfvA:
0.0		 5ef2P-2qfvA:
11.53
5ef2Q-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5ef2U-2qfvA:
undetectable
5ef2V-2qfvA:
undetectable		 5ef2U-2qfvA:
11.53
5ef2V-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 8 SER A 198
GLY A 276
THR A 107
HIS A 134
 None
 0.87A 5ef3L-2qfvA:
0.0
5ef3V-2qfvA:
undetectable		 5ef3L-2qfvA:
11.53
5ef3V-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.35A 5ef3P-2qfvA:
0.0
5ef3Q-2qfvA:
0.0		 5ef3P-2qfvA:
11.53
5ef3Q-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 276
THR A 107
HIS A 134
ILE A 131
SER A 198
 None
 1.39A 5ef3U-2qfvA:
undetectable
5ef3V-2qfvA:
undetectable		 5ef3U-2qfvA:
11.53
5ef3V-2qfvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 134
LYS A 272
PHE A 225
 None
 1.27A 5klaA-2qfvA:
undetectable		 5klaA-2qfvA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 237
SER A 198
ALA A 195
GLN A 230
 None
 0.83A 5n0tA-2qfvA:
3.7		 5n0tA-2qfvA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		5 / 9 ALA A 400
ILE A  27
LEU A  31
ILE A 335
ASN A 330
 None
 1.01A 5nunA-2qfvA:
undetectable		 5nunA-2qfvA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  72
SER A 307
ALA A 358
LEU A  36
 None
 1.07A 6dwnA-2qfvA:
undetectable		 6dwnA-2qfvA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 2qfv ISOCITRATE
DEHYDROGENASE [NADP]
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 301
ASP A 204
ASN A 359
 None
 0.77A 6gngB-2qfvA:
undetectable		 6gngB-2qfvA:
22.49