SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qfz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.44A 1v54A-2qfzA:
undetectable
1v54C-2qfzA:
undetectable		 1v54A-2qfzA:
19.66
1v54C-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.43A 1v54N-2qfzA:
undetectable
1v54P-2qfzA:
undetectable		 1v54N-2qfzA:
19.66
1v54P-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.47A 1v55A-2qfzA:
undetectable
1v55C-2qfzA:
undetectable		 1v55A-2qfzA:
19.66
1v55C-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.44A 2dyrA-2qfzA:
undetectable
2dyrC-2qfzA:
undetectable		 2dyrA-2qfzA:
19.66
2dyrC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.44A 2dyrN-2qfzA:
undetectable
2dyrP-2qfzA:
undetectable		 2dyrN-2qfzA:
19.66
2dyrP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 2dysA-2qfzA:
undetectable
2dysC-2qfzA:
undetectable		 2dysA-2qfzA:
19.66
2dysC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.47A 2dysN-2qfzA:
undetectable
2dysP-2qfzA:
undetectable		 2dysN-2qfzA:
19.66
2dysP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.48A 2eijA-2qfzA:
undetectable
2eijC-2qfzA:
undetectable		 2eijA-2qfzA:
19.66
2eijC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.47A 2eijN-2qfzA:
undetectable
2eijP-2qfzA:
undetectable		 2eijN-2qfzA:
19.66
2eijP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 2eikA-2qfzA:
1.8
2eikC-2qfzA:
undetectable		 2eikA-2qfzA:
19.66
2eikC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 2eikN-2qfzA:
undetectable
2eikP-2qfzA:
undetectable		 2eikN-2qfzA:
19.66
2eikP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.43A 2eilA-2qfzA:
undetectable
2eilC-2qfzA:
undetectable		 2eilA-2qfzA:
19.66
2eilC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.44A 2eilN-2qfzA:
undetectable
2eilP-2qfzA:
undetectable		 2eilN-2qfzA:
19.66
2eilP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.48A 2eimA-2qfzA:
2.2
2eimC-2qfzA:
undetectable		 2eimA-2qfzA:
19.66
2eimC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.39A 2eimN-2qfzA:
undetectable
2eimP-2qfzA:
undetectable		 2eimN-2qfzA:
19.66
2eimP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.43A 2einA-2qfzA:
2.2
2einC-2qfzA:
undetectable		 2einA-2qfzA:
19.66
2einC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.44A 2y69A-2qfzA:
undetectable
2y69C-2qfzA:
undetectable		 2y69A-2qfzA:
19.66
2y69C-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 5 GLN A 320
GLN A 279
ILE A 282
ARG A 278
 UNX  A1012 (-3.1A)
None
None
None
 1.34A 2z0aA-2qfzA:
undetectable		 2z0aA-2qfzA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 2zxwA-2qfzA:
undetectable
2zxwC-2qfzA:
undetectable		 2zxwA-2qfzA:
19.66
2zxwC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 2zxwN-2qfzA:
undetectable
2zxwP-2qfzA:
undetectable		 2zxwN-2qfzA:
19.66
2zxwP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 3abkA-2qfzA:
undetectable
3abkC-2qfzA:
undetectable		 3abkA-2qfzA:
19.66
3abkC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.47A 3abkN-2qfzA:
undetectable
3abkP-2qfzA:
undetectable		 3abkN-2qfzA:
19.66
3abkP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 3ag1A-2qfzA:
undetectable
3ag1C-2qfzA:
undetectable		 3ag1A-2qfzA:
19.66
3ag1C-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 3ag1N-2qfzA:
undetectable
3ag1P-2qfzA:
undetectable		 3ag1N-2qfzA:
19.66
3ag1P-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.48A 3ag2A-2qfzA:
undetectable
3ag2C-2qfzA:
undetectable		 3ag2A-2qfzA:
19.66
3ag2C-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.49A 3ag2N-2qfzA:
undetectable
3ag2P-2qfzA:
undetectable		 3ag2N-2qfzA:
19.66
3ag2P-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.49A 3ag3A-2qfzA:
undetectable
3ag3C-2qfzA:
undetectable		 3ag3A-2qfzA:
19.66
3ag3C-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 3ag3N-2qfzA:
undetectable
3ag3P-2qfzA:
undetectable		 3ag3N-2qfzA:
19.66
3ag3P-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.49A 3ag4A-2qfzA:
2.8
3ag4C-2qfzA:
undetectable		 3ag4A-2qfzA:
19.66
3ag4C-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.48A 3ag4N-2qfzA:
undetectable
3ag4P-2qfzA:
undetectable		 3ag4N-2qfzA:
19.66
3ag4P-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 3asnA-2qfzA:
undetectable
3asnC-2qfzA:
undetectable		 3asnA-2qfzA:
19.66
3asnC-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 MET A 367
LEU A 371
PRO A 328
MET A 427
 None
 0.92A 3hcnA-2qfzA:
undetectable		 3hcnA-2qfzA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		5 / 12 ALA A 418
LEU A 454
SER A 397
ILE A 399
LEU A 504
 None
 1.30A 3ia4C-2qfzA:
undetectable		 3ia4C-2qfzA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		3 / 3 ARG A 228
TRP A 232
ILE A 436
 None
 0.96A 4mwxA-2qfzA:
undetectable		 4mwxA-2qfzA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 5b1aN-2qfzA:
undetectable
5b1aP-2qfzA:
undetectable		 5b1aN-2qfzA:
19.66
5b1aP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.47A 5b1bN-2qfzA:
undetectable
5b1bP-2qfzA:
undetectable		 5b1bN-2qfzA:
19.66
5b1bP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 5b3sN-2qfzA:
undetectable
5b3sP-2qfzA:
undetectable		 5b3sN-2qfzA:
19.66
5b3sP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 5iy5A-2qfzA:
3.3
5iy5C-2qfzA:
undetectable		 5iy5A-2qfzA:
19.66
5iy5C-2qfzA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 5x19N-2qfzA:
undetectable
5x19P-2qfzA:
undetectable		 5x19N-2qfzA:
19.66
5x19P-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 5x1bN-2qfzA:
2.4
5x1bP-2qfzA:
undetectable		 5x1bN-2qfzA:
19.66
5x1bP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 5x1fN-2qfzA:
undetectable
5x1fP-2qfzA:
undetectable		 5x1fN-2qfzA:
19.66
5x1fP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 7 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.46A 5zcqN-2qfzA:
undetectable
5zcqP-2qfzA:
undetectable		 5zcqN-2qfzA:
19.66
5zcqP-2qfzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 5 PHE A 302
PRO A 285
MET A 287
VAL A 298
 None
 1.19A 6ekzA-2qfzA:
undetectable		 6ekzA-2qfzA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qfz TBC1 DOMAIN FAMILY
MEMBER 22A
(Homo
sapiens) 		4 / 6 ASP A 275
THR A 276
TYR A 277
HIS A 313
 None
 1.45A 6nknA-2qfzA:
undetectable
6nknC-2qfzA:
undetectable		 6nknA-2qfzA:
19.66
6nknC-2qfzA:
21.07