SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 2qg1 MULTIPLE PDZ DOMAIN
PROTEIN
(Homo
sapiens) 		6 / 12 GLY A1737
ALA A1760
ASP A1763
ILE A1726
ILE A1740
ILE A1754
 None
 1.32A 2nmzA-2qg1A:
undetectable		 2nmzA-2qg1A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 2qg1 MULTIPLE PDZ DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A1766
VAL A1775
LEU A1738
LEU A1736
ALA A1760
 None
 1.14A 4p65B-2qg1A:
undetectable
4p65D-2qg1A:
undetectable
4p65G-2qg1A:
undetectable
4p65H-2qg1A:
undetectable		 4p65B-2qg1A:
21.31
4p65D-2qg1A:
21.31
4p65G-2qg1A:
10.23
4p65H-2qg1A:
21.31