SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qg7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 6 ASN A 122
ILE A 350
ASN A 301
SER A 300
 SO4  A 600 (-3.5A)
None
None
None
 0.94A 1h7xA-2qg7A:
undetectable		 1h7xA-2qg7A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 6 ASN A 122
ILE A 350
ASN A 301
SER A 300
 SO4  A 600 (-3.5A)
None
None
None
 0.92A 1h7xB-2qg7A:
undetectable		 1h7xB-2qg7A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 6 ASN A 122
ILE A 350
ASN A 301
SER A 300
 SO4  A 600 (-3.5A)
None
None
None
 0.94A 1h7xC-2qg7A:
undetectable		 1h7xC-2qg7A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 6 ASN A 122
ILE A 350
ASN A 301
SER A 300
 SO4  A 600 (-3.5A)
None
None
None
 0.93A 1h7xD-2qg7A:
undetectable		 1h7xD-2qg7A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		3 / 3 ILE A 123
ILE A 115
THR A 121
 None
 0.57A 1rg7A-2qg7A:
undetectable		 1rg7A-2qg7A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 8 HIS A 294
ASP A 363
THR A 239
ASP A 296
 None
 1.21A 1rg9B-2qg7A:
undetectable		 1rg9B-2qg7A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 5 LEU A 297
ILE A 302
ILE A 202
ALA A 203
 None
 0.77A 2i2zA-2qg7A:
undetectable		 2i2zA-2qg7A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 9 ILE A 415
VAL A 279
CYH A 283
LYS A 284
 None
 1.07A 2vufB-2qg7A:
1.1		 2vufB-2qg7A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		5 / 12 LEU A 236
SER A 234
SER A 288
CYH A 283
LEU A 206
 None
 1.38A 2zlcA-2qg7A:
undetectable		 2zlcA-2qg7A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		5 / 12 SER A 158
GLY A 177
ARG A 139
VAL A  94
ILE A 179
 None
None
SO4  A 600 (-4.4A)
None
None
 1.37A 3jb2A-2qg7A:
undetectable		 3jb2A-2qg7A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		3 / 3 ALA A 361
ARG A 360
LYS A 207
 None
 0.79A 3kp3B-2qg7A:
undetectable		 3kp3B-2qg7A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MES_A_DMEA427_1
(CHOLINE KINASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		6 / 10 ASP A 296
GLU A 370
TRP A 421
TRP A 424
PHE A 436
TYR A 441
 None
 0.49A 3mesA-2qg7A:
29.9		 3mesA-2qg7A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MES_B_DMEB427_1
(CHOLINE KINASE)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		6 / 10 ASP A 296
GLU A 370
TRP A 421
TRP A 424
PHE A 436
TYR A 441
 None
 0.50A 3mesB-2qg7A:
30.1		 3mesB-2qg7A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		5 / 12 LEU A 236
SER A 234
SER A 288
CYH A 283
LEU A 206
 None
 1.37A 3vt3A-2qg7A:
undetectable		 3vt3A-2qg7A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		3 / 3 ASP A 296
TRP A 378
SER A 300
 None
 1.07A 4lrhA-2qg7A:
undetectable		 4lrhA-2qg7A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		5 / 12 GLY A 442
ILE A 149
THR A 239
GLU A 370
GLY A 422
 None
SO4  A 600 (-4.8A)
None
None
None
 0.84A 5veuH-2qg7A:
undetectable		 5veuH-2qg7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		3 / 3 ILE A 193
ASN A 366
CYH A 293
 None
 0.76A 6bp4A-2qg7A:
undetectable		 6bp4A-2qg7A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_2
(-)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		4 / 6 TRP A 421
HIS A 367
ASN A 369
GLU A 387
 None
 1.38A 6gneA-2qg7A:
undetectable		 6gneA-2qg7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 2qg7 ETHANOLAMINE KINASE
PV091845
(Plasmodium
vivax) 		5 / 12 PHE A 368
LEU A 298
GLY A 373
ILE A 410
SER A 299
 None
 1.07A 6mhtA-2qg7A:
undetectable		 6mhtA-2qg7A:
23.19