SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qgg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		3 / 3 ASP A 108
TYR A 105
GLU A 103
 None
UNL  A 202 (-4.2A)
None
 0.74A 1vm1A-2qggA:
undetectable		 1vm1A-2qggA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		4 / 5 ILE A 174
ILE A 150
ILE A 157
MET A 141
 None
 0.80A 1zgyA-2qggA:
undetectable		 1zgyA-2qggA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		4 / 5 VAL A  29
LEU A  17
ILE A  89
VAL A  58
 None
 0.97A 4a9kB-2qggA:
undetectable		 4a9kB-2qggA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		4 / 7 ILE A  47
LEU A  17
LYS A  59
GLY A  25
 None
 0.78A 4hajA-2qggA:
undetectable		 4hajA-2qggA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		4 / 8 ILE A  47
LEU A  17
LYS A  59
GLY A  25
 None
 0.89A 4hb6A-2qggA:
undetectable		 4hb6A-2qggA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		4 / 8 ILE A  47
LEU A  17
LYS A  59
GLY A  25
 None
 0.73A 4hb8A-2qggA:
undetectable		 4hb8A-2qggA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		5 / 11 ALA A  99
ASP A 102
MET A 141
LEU A 109
VAL A 167
 None
 1.39A 4kyaA-2qggA:
undetectable		 4kyaA-2qggA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		5 / 10 ALA A  99
ASP A 102
MET A 141
LEU A 109
VAL A 167
 None
 1.41A 4kyaC-2qggA:
undetectable		 4kyaC-2qggA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2qgg 16S RRNA-PROCESSING
PROTEIN RIMM
(Acinetobacter
calcoaceticus) 		5 / 12 TRP A  45
SER A  87
GLY A  80
SER A  83
VAL A  29
 None
 1.08A 6a94A-2qggA:
undetectable		 6a94A-2qggA:
18.80