SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qgo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 10 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.45A 1a52A-2qgoA:
undetectable		 1a52A-2qgoA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 10 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.42A 1a52B-2qgoA:
undetectable		 1a52B-2qgoA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 9 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.41A 1ereA-2qgoA:
undetectable		 1ereA-2qgoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 9 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.41A 1ereB-2qgoA:
undetectable		 1ereB-2qgoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 9 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.40A 1ereC-2qgoA:
undetectable		 1ereC-2qgoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 9 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.42A 1ereD-2qgoA:
undetectable		 1ereD-2qgoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 10 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.38A 1qkuA-2qgoA:
undetectable		 1qkuA-2qgoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 10 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.38A 1qkuB-2qgoA:
undetectable		 1qkuB-2qgoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 10 ALA A  12
LEU A  97
LEU A  99
ILE A  74
LEU A  22
 None
 1.38A 1qkuC-2qgoA:
undetectable		 1qkuC-2qgoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 12 ILE A  74
ILE A  29
SER A  51
LEU A  84
ILE A  66
 None
 1.13A 3cd2A-2qgoA:
undetectable		 3cd2A-2qgoA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		4 / 7 ASP A 107
PHE A  50
SER A  51
HIS A  49
 None
 1.42A 4o4dA-2qgoA:
undetectable		 4o4dA-2qgoA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_C_MTXC604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 12 ALA A  12
LEU A  97
SER A 101
LEU A  84
THR A   9
 None
 1.26A 4q0dC-2qgoA:
undetectable		 4q0dC-2qgoA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_D_MTXD604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		5 / 12 ALA A  12
LEU A  97
SER A 101
LEU A  84
THR A   9
 None
 1.26A 4q0dD-2qgoA:
undetectable		 4q0dD-2qgoA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2qgo PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
acidophilus) 		4 / 5 ARG A  19
ILE A  21
GLY A 115
ILE A 112
 None
 0.88A 5dzki-2qgoA:
undetectable
5dzkj-2qgoA:
undetectable
5dzkx-2qgoA:
undetectable		 5dzki-2qgoA:
18.48
5dzkj-2qgoA:
18.48
5dzkx-2qgoA:
50.00